Kids' cough study: antibiotics or steroids – placebo may be just as good

NCT ID NCT07582549

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether two common treatments—an inhaled steroid (fluticasone) for dry cough and an antibiotic (amoxicillin-clavulanic acid) for wet cough—actually help children with a cough lasting more than four weeks. About 100 generally healthy children will be randomly assigned to receive the real treatment or a placebo, and neither families nor doctors will know which. The goal is to see if these treatments significantly reduce or stop the cough compared to placebo, which could improve treatment guidelines and avoid unnecessary medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fluticasone propionate (inhaled corticosteroid) or amoxicillin-clavulanic acid (antibiotic)

What this could lead to

If successful, this could provide clear evidence on whether common treatments like inhaled steroids or antibiotics actually help children with persistent cough, reducing unnecessary medication use.

What could go wrong

This is a relatively small trial (100 children) and results may not apply to all kids. The treatments may not work better than placebo, and side effects like allergic reactions are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Cough

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Study Site: Tampere University Hospital (TAYS), Children's and Adolescents' Hospital Outpatient Paediatrics Unit P.O. Box 2000, FI-33521 Tampere, Finland

    RECRUITING

    Tampere, Finland

    Contact Phone: •••-•••-•••• Email: •••••@•••••