Kids' cough study: antibiotics or steroids – placebo may be just as good
NCT ID NCT07582549
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether two common treatments—an inhaled steroid (fluticasone) for dry cough and an antibiotic (amoxicillin-clavulanic acid) for wet cough—actually help children with a cough lasting more than four weeks. About 100 generally healthy children will be randomly assigned to receive the real treatment or a placebo, and neither families nor doctors will know which. The goal is to see if these treatments significantly reduce or stop the cough compared to placebo, which could improve treatment guidelines and avoid unnecessary medication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Fluticasone propionate (inhaled corticosteroid) or amoxicillin-clavulanic acid (antibiotic)
- What this could lead to
- If successful, this could provide clear evidence on whether common treatments like inhaled steroids or antibiotics actually help children with persistent cough, reducing unnecessary medication use.
- What could go wrong
- This is a relatively small trial (100 children) and results may not apply to all kids. The treatments may not work better than placebo, and side effects like allergic reactions are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Study Site: Tampere University Hospital (TAYS), Children's and Adolescents' Hospital Outpatient Paediatrics Unit P.O. Box 2000, FI-33521 Tampere, Finland
RECRUITINGTampere, Finland
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