National Institute Of Diabetes And Digestive And Kidney Diseases (niddk)
Clinical trials sponsored by National Institute Of Diabetes And Digestive And Kidney Diseases (niddk), explained in plain language.
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Could new pills slow down type 1 diabetes?
Disease control OngoingThis study is testing whether two oral medications can help preserve the body's remaining ability to produce insulin in people recently diagnosed with type 1 diabetes. It involves 78 participants aged 12-35 who were diagnosed within the last 100 days. Participants will take one o…
Phase: PHASE2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Lifeline drug access for rare fat disorder patients
Disease control OngoingThis study provides continued access to the drug metreleptin for people with partial lipodystrophy, a rare condition that causes severe diabetes and high blood fats. It is for patients who have already benefited from the drug in past NIH studies but cannot get it through regular …
Phase: PHASE2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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Lifeline for rare disease patients denied access to vital drug
Disease control OngoingThis study provides continued access to the drug metreleptin for people with a rare condition called generalized lipodystrophy who have previously received it through NIH research and cannot get it through normal channels in their home country. It aims to monitor the long-term sa…
Phase: PHASE3 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Double-Drug attack on diabetes: can new combo save insulin cells?
Disease control OngoingThis study is testing whether giving two immune-modulating drugs (rituximab-pvvr followed by abatacept) is better than one drug alone for people recently diagnosed with type 1 diabetes. The main goal is to see if the combination helps the body preserve its own ability to make ins…
Phase: PHASE2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Researchers track Decades-Long impact of diabetes on native american kidneys
Knowledge-focused TerminatedThis study follows American Indians with type 2 diabetes to understand the long-term effects of a previous kidney treatment trial. Researchers are observing how kidney disease progresses over many years through regular tests, scans, and optional biopsies. No new treatment is prov…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:56 UTC
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10-Year watch: what happens after hepatitis c is cured?
Knowledge-focused OngoingThis study aims to understand the long-term health of people who have been cured of chronic Hepatitis C. Researchers will follow 121 participants for up to 10 years to see if cured patients still develop liver complications, cancer, or other health problems. The goal is to learn …
Phase: PHASE4 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists hunt for diabetes genes in major study
Knowledge-focused TerminatedThis study aims to discover the specific genes and biological pathways that influence a person's risk of developing type 2 diabetes and related health problems like kidney and eye disease. Researchers will collect health information, blood samples, and genetic data from over 2,00…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:25 UTC