Hope for rare fat disorder: drug keeps working in Long-Term study

NCT ID NCT02262806

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 34 times

Summary

This study gives the drug metreleptin to people with partial lipodystrophy, a rare condition that causes abnormal fat storage, high blood fats, and diabetes. Participants have already shown improvement from metreleptin in earlier studies and cannot get the drug elsewhere. The goal is to see if the drug remains safe and effective over time, with regular check-ups every 6 to 12 months.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.