Nanjing First Hospital, Nanjing Medical University

This study tests whether a super high-pressure balloon or a special shockwave device (intravascular lithotripsy) works better to crack open severely calcified coronary arteries before placing a stent. About 78 adults with hardened heart arteries will be randomly assigned to one o…

This study looks at whether treating Helicobacter pylori (Hp) infection can also help improve metabolic syndrome—a group of conditions like high blood sugar, unhealthy cholesterol, and excess belly fat. About 120 adults with both Hp infection and newly diagnosed metabolic syndrom…

This study tests whether adding a low-dose anti-inflammatory drug called colchicine to standard heart treatments can lower the risk of major heart problems like heart attacks and strokes. About 3,800 adults with stable coronary artery disease and non-blocking plaque will be rando…

This study tests a new, less invasive heart valve implant for people with severe aortic regurgitation (a leaky heart valve). About 210 participants will be randomly assigned to get the new valve or standard care. The main goal is to see if the implant reduces the risk of death, s…

This study is for people with moderate to severe narrowing of brain arteries who have not had a stent or clot removal. It tests whether improving cholesterol levels can lower the chance of having a stroke. About 180 adults will be followed over time to see how cholesterol managem…

This study compares two approaches for treating re-narrowed heart stents: using special imaging to guide the procedure versus standard X-ray guidance. About 1,500 people with a first-time re-blockage of a drug-coated stent will take part. The goal is to see which method leads to …

This study aims to see if special PET scans using different radioactive tracers can accurately find and stage neuroblastoma and pheochromocytoma/paraganglioma tumors. About 30 people aged 1 to 70 with suspected or confirmed disease will receive an injection of a tracer and then h…

This study compares a new laser-assisted ultrasound method to standard ultrasound for placing IVs in people having heart surgery. Researchers want to see if the laser tool helps nurses get the IV in on the first try more often. About 100 adults aged 18-80 will take part.

This study tests different amounts of a long-acting numbing medicine (liposomal bupivacaine) injected near the knee to control pain after surgery. The goal is to find the dose that provides good pain relief without weakening the thigh muscle too much. About 63 adults having knee …

This study examines tiny RNA molecules in the blood of 300 adults who had a stroke and received a procedure to remove the clot. Researchers want to see if certain RNA patterns can help predict how well patients recover. The goal is to find new markers that could guide future stro…

This study is tracking 5,000 adults hospitalized for an ischemic stroke to see how different treatment strategies affect their recovery. Researchers will collect medical records and brain scans to build models that predict outcomes. The goal is to learn which treatments work best…

This study compares blood RNA patterns between 500 people who recently had a stroke and healthy volunteers. The goal is to find RNA molecules that can help doctors detect strokes earlier and predict how well patients will recover. No new treatments are being tested; this is a res…

This study compares two different nerve block techniques to see which one provides better pain relief during a procedure to locate lung nodules. Researchers will enroll 50 adults aged 18-80 who are scheduled for a CT-guided lung nodule localization. The goal is to understand how …