Nanjing First Hospital, Nanjing Medical University

This study compares two ways to place heart stents in people with diabetes: one using special imaging (IVUS or OCT) and the other using standard X-ray. The goal is to see if the imaging method reduces heart-related deaths, heart attacks, or the need for repeat procedures. About 1…

This study looks at 180 adults with moderate to severe narrowing of brain arteries who have high LDL cholesterol. Researchers want to see if improving cholesterol management can lower the chance of having a stroke. Participants will not receive any experimental treatment; instead…

This study looks at whether treating Helicobacter pylori (Hp), a common stomach infection, can also help improve metabolic syndrome (high blood sugar, cholesterol, and weight). Researchers will give standard Hp treatment alone or with probiotics or berberine to 120 adults. They w…

This study compares a new, less invasive heart valve implant (TAVR) with standard medication for people who have severe aortic regurgitation, a condition where the heart's aortic valve doesn't close properly. The trial will enroll 210 participants across multiple centers. The goa…

This study tests two ways to break up heavy calcium buildup in heart arteries before placing a stent: a super high-pressure balloon versus a special shockwave balloon (lithotripsy). About 78 adults with severe coronary artery disease will be randomly assigned to one method. The g…

This study tests whether adding low-dose colchicine (0.5 mg daily) to standard heart treatments can lower the risk of major heart problems like heart attacks and strokes. About 3,800 adults with stable coronary artery disease and non-flow-limiting plaque will be randomly assigned…

This study compares two methods for guiding a second stent procedure in people whose drug-coated stents have re-narrowed. One method uses standard X-ray (angiography), the other adds detailed imaging from inside the artery. The goal is to see which approach leads to fewer major h…

This study is testing whether special PET scans using targeted tracers can accurately find and stage neuroblastoma and pheochromocytoma/paraganglioma tumors. About 30 people aged 1 to 70 will receive an injection of a radioactive tracer and then have a PET scan. The scan results …

This study tests whether a laser-assisted ultrasound device helps doctors place IV lines more successfully on the first try in patients having heart surgery. One hundred adults aged 18 to 80 will be randomly assigned to get either standard ultrasound guidance or laser-assisted ul…

This study tests different volumes of liposomal bupivacaine, a long-acting painkiller, injected near the nerve in the thigh to numb the knee during surgery. The goal is to find the dose that provides good pain control while minimizing leg muscle weakness. Sixty-three adults havin…

This study is testing whether a detailed CT scan of the heart and arteries can better predict future heart attacks, heart failure, or dangerous heart rhythms in people who have already had a heart attack and a stent placed. Researchers will follow 1,000 patients for up to five ye…

This study is analyzing blood samples from 500 people who recently had a stroke and comparing them to healthy volunteers. Researchers are looking for specific RNA molecules that could serve as biomarkers to detect stroke and predict how well patients will recover. The goal is to …

This study examines blood samples from 300 adults who had a stroke and received a procedure to remove the clot. Researchers look for specific RNA molecules that change before and after treatment. The goal is to find markers that can help predict how well patients will recover and…

This study is collecting information from 5,000 people hospitalized for ischemic stroke to see how different treatments affect their recovery. Researchers will track outcomes like disability and stroke recurrence over up to 24 months. The goal is to build models that help predict…

This study compares two types of nerve blocks used before CT-guided lung nodule localization. Researchers will use 3D CT scans to see how far the numbing medicine spreads with each method. Fifty adults aged 18-80 will take part. The goal is to understand which block works better,…