Ku Leuven

This study tests a program called I-CONNECT for adults aged 65 and older who have depression or bipolar disorder plus at least two chronic physical conditions like diabetes or high blood pressure. The program assigns a care coordinator who works with the patient's doctor, psychia…

This study tests a digital tool that gives doctors real-time, guideline-based advice on prescribing antibiotics. About 48 general practices in Belgium will use the tool during patient visits. The goal is to see if it reduces unnecessary antibiotic use and helps fight antibiotic r…

This study tests whether using a fluid enriched with hyaluronan during embryo transfer can increase the chance of a pregnancy that lasts past 12 weeks. It involves 400 women under 40 who have not had a successful pregnancy after previous IVF attempts. The main goal is to see if t…

This study tests whether a home-based breathing muscle training program can reduce hospital readmissions and deaths in people recovering from a severe COPD flare-up. About 358 adults who were hospitalized for at least 3 days will either receive usual care or add daily breathing e…

This study aims to improve how doctors tell the difference between borderline ovarian tumors and early-stage invasive ovarian cancer before surgery. Researchers will test a panel of nine blood-based biomarkers in 400 women with suspicious ovarian cysts. If successful, this could …

This study tests a new rapid blood test done at the patient's bedside to quickly rule out a type of heart attack (NSTEMI) in people with chest pain. About 1,550 adults visiting the emergency room will be randomly assigned to either the new rapid test or the standard lab test. The…

This study aims to see if certain chemicals (oncometabolites) in a person's breath and blood can spot early-stage gastro-esophageal cancer. Researchers will compare samples from 1,000 people, including those with cancer, those with Barrett's esophagus (a precancerous condition), …

This study looks at whether inhaling menthol can quickly relieve shortness of breath in healthy adults and people with COPD. Researchers will measure brain activity and breathing to understand how menthol works. The goal is to find a simple, drug-free way to ease breathing discom…

This study looks at whether a team-based rehab program called Revita can help people with long-term back or spine problems. About 90 adults will take part in exercise and therapy sessions. Researchers will measure changes in pain, daily function, and quality of life before and af…

This study looks at whether doing a 12-week exercise program with your feet turned outward (toes-out) helps people with mid-portion Achilles tendinopathy more than the usual neutral-foot position. About 60 adults aged 18–65 with Achilles pain will be followed for 6 months. Resear…

This study looks at whether taking CBD (a compound from cannabis) can improve sleep quality after doing intense exercise late in the evening. Twenty healthy adults will have their sleep monitored in a lab after taking either CBD or a placebo. The goal is to see if CBD helps peopl…

This study tests whether adding one hour of arm-hand exercises daily (5 days a week for 4 weeks) to usual care helps stroke patients regain arm function. 80 people who had a stroke within the last 5 months will be randomly assigned to either the extra arm-hand program or a lower-…

This small study in Uganda looks at how meals made with local fruits and vegetables affect blood sugar and fat levels in people with type 2 diabetes. Eight participants will eat five different test meals over five weeks, with blood samples taken over three hours after each meal. …

This study looks at two different ways of doing bed-cycling exercises for patients in the intensive care unit (ICU) who are weak from being in bed for a long time. The goal is to see which type—steady moderate cycling or short bursts of harder cycling with rest periods—is safer a…

This study takes tiny tissue samples from the rectum of people with Irritable Bowel Syndrome (IBS) and healthy volunteers to measure how gut nerves work. Researchers will use special imaging and genetic tests to see how these nerves react to different substances and foods. The go…

This study follows 150 people treated for rectal cancer to understand why some have lasting bowel symptoms and how it affects their quality of life. Researchers will use diaries and questionnaires to track symptoms a year after surgery or active surveillance. The goal is to creat…

This study aims to see if a new clinical test, the Ad-AHA Stroke, accurately reflects how stroke survivors use both hands together in everyday activities. Researchers will compare test scores with real-world data from wrist-worn sensors worn for three days. 32 adults who had a st…

This study uses a 20-25 minute survey to find out which features of diagnostic tests for gastro-esophageal cancer matter most to patients and the general public. Researchers aim to understand preferences and regional differences to improve screening decisions. About 2,200 adults …

This study looks at different forms of IgE (a protein involved in allergic reactions) in healthy volunteers and people with conditions like severe allergies, chronic hives, mastocytosis, and immune deficiencies. Researchers aim to understand how these IgE variations relate to hea…

This study tests an artificial intelligence (AI) algorithm that uses wearable sensors to detect freezing of gait—a sudden inability to move while walking—in people with Parkinson's disease. The goal is to see if the AI works accurately in home settings, not just in a lab. About 1…

This study aims to improve how doctors monitor chronic lung diseases by using a computer model to predict changes in lung function. Researchers will collect data from 4,000 adults with chronic respiratory conditions to see if the model can accurately forecast lung function and id…

This study checks if a new smartphone-based method called ESDAM can accurately measure daily food and drink intake. Researchers will compare ESDAM results with objective lab tests in 115 healthy adults. The goal is to see if this app can be a reliable tool for future nutrition re…

This study is developing a new smartphone diary to help rectal cancer patients better track and report their bowel symptoms. Researchers will work with 158 patients and experts to make sure the diary captures all important symptoms and is easy to use. The goal is to improve how d…

This study looks at how different breathing muscle training methods affect patients who are struggling to come off a mechanical ventilator in the ICU. Researchers will measure changes in muscle strength and structure using pressure tests, ultrasounds, and small muscle samples. Th…