Irccs Azienda Ospedaliero-universitaria Di Bologna

This study looks at two ways to pace the heart in 1260 adults with atrioventricular block (a condition where the heart's electrical signals are delayed or blocked). One method stimulates the heart's natural conduction system; the other is the standard approach. The goal is to see…

This study compares two medical devices used to recondition lungs from marginal donors before transplant. About 20 adults needing double lung transplants will take part. The goal is to see which device helps more lungs get accepted for transplant and improves recovery.

This study tests whether using a laser to clear re-narrowed heart stents works better than standard balloon treatment. About 1,260 adults with a drug-coated stent that has narrowed again will be randomly assigned to one of the two methods. The goal is to see which approach reduce…

This study will test whether a new molecular test (RT-PCR) can diagnose Rickettsia infections earlier than current methods. Researchers will study 800 people with suspected infection, using blood and tissue samples already collected during routine care. The goal is to see if the …

This study tests a special wearable device that watches newborns' heart rate and breathing during the first few days of life. The goal is to catch early warning signs of sudden unexpected postnatal collapse (SUPC) before it happens. About 5,000 healthy newborns will wear the devi…

This study watches surgeons as they operate to see how much physical strain they experience. Ten experienced surgeons will wear motion-capture suits and muscle sensors during bowel or prostate surgery using different methods (standard keyhole or robotic systems). The goal is to f…

This study follows 300 children who had cancer to see how a stem cell transplant before puberty affects their final height and hormone levels. Researchers compare those who received the transplant with those who did not. The goal is to understand the long-term impact on growth an…

This study looks at why some high-grade ovarian cancers do not respond well to standard chemotherapy. Researchers will use a special device called a U-Cup bioreactor to test tumor tissue from 120 women before they start treatment. The goal is to find ways to predict resistance an…

This study will collect data from 2000 adults having colorectal surgery with the Hugo RAS robot. Researchers will track complications, recovery, and long-term results to see how safe and effective the system is. The goal is to provide real-world evidence to improve minimally inva…

This study aims to understand why some head and neck cancers become resistant to standard treatments. Researchers will collect tumor samples from 120 patients and create special mouse models to study the cancer's biology. By analyzing these samples, they hope to identify new targ…

This study looks at whether measuring two substances in the blood, IL-18 and IL-18BP, can help doctors tell apart rare inflammatory diseases like systemic juvenile idiopathic arthritis from other fever-causing illnesses. Researchers will study 9 children aged 2 to 18 who have cer…