New trial tests gentler surgery for ovarian cysts to save fertility
NCT ID NCT07666412
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two surgical techniques for ovarian endometrioma—standard cyst removal (cystectomy) versus a newer method using argon plasma coagulation (APC) to vaporize the cyst lining. The goal is to see which better preserves ovarian reserve, measured by antral follicle count and AMH levels, and reduces recurrence. 146 women aged 18-40 with symptomatic endometriomas will be followed for 12 months after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Argon Plasma Coagulation (APC) ablation procedure
What this could lead to
If APC works better, it could offer a safer surgical option that preserves more healthy ovarian tissue and reduces the risk of infertility after endometrioma surgery.
What could go wrong
This is an early randomized trial with no prior direct comparison, so results may not confirm superiority. There is also a risk of cyst recurrence with APC due to leftover endometriotic tissue.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, 40138, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••