New blood markers may speed up diagnosis of childhood arthritis and fevers

NCT ID NCT06718049

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at two substances in the blood, IL-18 and IL-18BP, to see if they can help doctors tell apart different causes of fever in children. Researchers will measure these levels in 9 children with conditions like juvenile arthritis, autoinflammatory diseases, or serious infections. The goal is to find new markers that could lead to faster and more accurate diagnoses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test to help doctors quickly diagnose rare inflammatory diseases in children, reducing delays in treatment.
What could go wrong
This is a very small observational study with only 9 participants, so results may not apply broadly. It is not testing a treatment, only exploring potential markers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RECURRENT AUTOINFLAMMATORY FEVER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna

    Bologna, Bologna, 40138, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.