Institute Of Liver And Biliary Sciences, India

This trial tests whether using a more relaxed ROTEM threshold (a blood clotting test) can safely reduce the amount of blood products given to people with severe liver disease before medical procedures. Participants have cirrhosis or acute-on-chronic liver failure and will be rand…

This study looks at whether a plant-based (vegan) diet can help children with autoimmune hepatitis achieve disease remission. Researchers will compare a vegan diet to a standard high-protein diet over 180 days in 40 newly diagnosed children. The goal is to see if diet changes can…

This pilot study tests whether giving a combination of two growth factors (G-CSF and darbepoetin) in single or repeated cycles can improve immune function in people with early decompensated cirrhosis. Sixty participants will be randomly assigned to receive either the growth facto…

This study tests whether a standard volume of plasma exchange (blood filtering) works as well as a high volume in children aged 3 to 18 with acute liver failure. The goal is to see which approach helps more children survive without needing a liver transplant by day 21. Forty part…

This study compares an Indianized version of the Mediterranean diet to a standard low-fat diet for reducing liver fat in overweight children and teens with a fatty liver condition called MASLD. About 134 participants aged 8 to 18 will follow one of the two diets for 180 days. The…

This study will follow 100 adults with chronic liver disease who are hospitalized for sudden worsening of their condition. Researchers will track organ failure, recovery, and whether patients need a liver transplant or die within 6 months. The goal is to better understand how the…

This study aims to create a nationwide registry of Indian children with hepatic glycogen storage diseases (GSDs), a group of inherited metabolic disorders affecting the liver and muscles. By collecting genetic, clinical, and outcome data from 250 children, researchers hope to map…

This study looks at whether certain gene variations in the donor and the recipient influence how much fat builds up in the new liver after a living-donor transplant for MASH-related cirrhosis. Researchers will compare genetically related and unrelated donor-recipient pairs to sep…

This trial studies whether omitting a routine magnetic resonance cholangiopancreatography (MRCP) scan in healthy living liver donors affects the rate of bile duct complications in transplant recipients. About 100 donors aged 18–55 will be randomly assigned to receive or skip the …

This study looks at how often staging laparoscopy – a small camera operation – finds cancer spread that modern scans miss in liver, pancreas, and bile duct cancers. Researchers will review data from 350 patients treated between 2012 and 2026. The goal is to see if this extra step…

This study tracks 100 adults with chronic liver disease who are receiving a liver transplant. Researchers will measure their bone mineral density before surgery and again at 3 and 6 months after, using a special X-ray scan called DEXA. The goal is to understand how bone health ch…

This study looks at how two different proteins—whey and egg white—affect blood ammonia levels in people with advanced liver disease caused by alcohol. High ammonia can harm brain function. Fifty patients will try both proteins on separate days, and their blood and thinking skills…

This study tracks 1,000 patients undergoing major liver, pancreas, or bile duct surgery to see if the time it takes for their albumin levels to return to normal can predict complications and length of hospital stay. Albumin is a protein that drops after surgery due to inflammatio…

This study looks at how liver transplantation impacts sexual function and quality of life in 100 married men with chronic liver disease. Researchers will use questionnaires to measure sexual dysfunction before and after transplant. The goal is to better understand recovery and im…

This study aims to find out if certain Helicobacter bacteria (like H. pylori) are more common in people with biliary tract cancer than in those with non-cancerous gallbladder issues. Researchers will test tissue samples from 250 participants, including cancer patients, people wit…