Your genes may decide your new Liver's fate after MASH transplant

NCT ID NCT07685353

First seen Jul 06, 2026 · Last updated Jul 22, 2026 · Updated 3 times

Summary

This study looks at whether certain gene variations in the donor and the recipient influence how much fat builds up in the new liver after a living-donor transplant for MASH-related cirrhosis. Researchers will compare genetically related and unrelated donor-recipient pairs to separate genetic from environmental effects. The goal is to understand why fatty liver disease sometimes returns after transplant, which could eventually help improve long-term outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If certain gene variants are linked to fat recurrence, doctors could better match donors and recipients to protect the new liver.
What could go wrong
This is an observational study with only 50 participants, so findings may not apply to everyone. Genetic factors are just one piece of a complex puzzle.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Liver and Biliary Sciences

    RECRUITING

    New Delhi, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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