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Home workouts may boost fitness in liver disease

NCT ID NCT06892366

Disease control Sponsor: Hacettepe University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This trial tests whether 8 weeks of home-based exercise can improve physical fitness, muscle strength, and quality of life in adults with chronic liver disease. Participants are split into three groups: aerobic exercise, aerobic plus resistance exercise, or a control group receiving physical activity advice. Researchers measure oxygen use, muscle size and strength, frailty, fatigue, and lifestyle habits before and after the program. The goal is to see if a supervised home routine can offer meaningful health benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Home-based aerobic and resistance exercise programs
What this could lead to
If effective, this could offer a practical, home-based exercise plan to improve fitness, muscle strength, and quality of life for people with chronic liver disease.
What could go wrong
The trial is small and early, and results may not apply to all patients. Exercise may be hard to sustain, and some participants might not see significant benefits.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

39 people

The number who actually took part.

Started

Jun 2022

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being followed up for chronic liver disease or listed on the liver transplant waiting list at the Hacettepe University Department of Internal Medicine, Division of Gastroenterology. * Owning and being able to use a smartphone. * Aged between 18 and 70 years. * Receiving primary prophylactic treatment for gastroesophageal varices. * Willingness to participate in the study. Exclusion Criteria: * Inability to own or use a smartphone. * Participation in an exercise training program within the last year. * Previous liver transplantation. * High-risk varices without beta-blocker treatment. * Presence of persistent hepatic encephalopathy. * Hepatic hydrothorax. * Pulmonary vascular complications of portal hypertension. * Chronic renal failure requiring dialysis. * Hemoglobin level below 10 g/dL. * Creatinine level above 2 mg/dL. * Human Immunodeficiency Virus (HIV) infection. * Presence of hepatocellular carcinoma (HCC). * Recent acute myocardial infarction. * Uncontrolled arrhythmias causing symptomatic hemodynamic instability. * Contraindications to maximal exercise testing. * Physical or orthopedic conditions preventing home-based exercise training. * Lack of willingness to participate in the study.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver End Stage Liver Disease Fibrosis Motor Activity Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic liver disease and cirrhosis

Contacts and locations

Locations

  • Hacettepe University Faculty of Physical Therapy and Rehabilitation

    Ankara, Altındağ, 06100, Turkey (Türkiye)

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