Could growth factors help repair the liver in cirrhosis?

NCT ID NCT07002827

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether giving a combination of two growth factors (G-CSF and darbepoetin) in single or repeated cycles can improve immune function in people with early decompensated cirrhosis. Sixty participants will be randomly assigned to receive either the growth factor combination or standard medical care. The main goal is to see changes in immune cell activity over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Granulocyte colony stimulating factor (G-CSF) and darbepoetin

What this could lead to

If successful, this could point toward a new way to boost the immune system and slow liver disease progression in people with early decompensated cirrhosis.

What could go wrong

This is a small pilot study with only 60 participants, so results may not apply to everyone. The treatment involves growth factors, which can cause side effects like bone pain or allergic reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic liver failure cirrhosis of liver

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Liver & Biliary Sciences (ILBS)

    RECRUITING

    New Delhi, National Capital Territory of Delhi, 110070, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••