New blood test could cut unnecessary transfusions in liver patients
NCT ID NCT07437755
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a new method using ROTEM (a rapid blood clotting test) to standard care for deciding whether to give blood products before high-risk procedures in patients with decompensated liver cirrhosis. The goal is to see if the ROTEM-guided approach reduces the number of patients receiving transfusions while keeping bleeding complications low. About 116 adults will be randomly assigned to either the ROTEM-guided strategy or usual care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Blood products transfusion (platelets, fresh frozen plasma, cryoprecipitate) guided by ROTEM testing
- What this could lead to
- If successful, this could lead to fewer unnecessary blood transfusions and safer procedures for patients with liver cirrhosis.
- What could go wrong
- This is a small, single-center trial, so results may not apply broadly. The ROTEM-guided approach may not reduce bleeding or transfusions as hoped.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institute of Gastroenterology and Hepatology
RECRUITINGIași, Iaşi, 700111, Romania
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