New blood test could cut unnecessary transfusions in liver patients
NCT ID NCT07437755
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a new method using ROTEM (a rapid blood clotting test) to standard care for deciding whether to give blood products before high-risk procedures in patients with decompensated liver cirrhosis. The goal is to see if the ROTEM-guided approach reduces the number of patients receiving transfusions while keeping bleeding complications low. About 116 adults will be randomly assigned to either the ROTEM-guided strategy or usual care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Blood products transfusion (platelets, fresh frozen plasma, cryoprecipitate) guided by ROTEM testing
What this could lead to
If successful, this could lead to fewer unnecessary blood transfusions and safer procedures for patients with liver cirrhosis.
What could go wrong
This is a small, single-center trial, so results may not apply broadly. The ROTEM-guided approach may not reduce bleeding or transfusions as hoped.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Institute of Gastroenterology and Hepatology
RECRUITINGIași, Iaşi, 700111, Romania
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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