Insel Gruppe Ag, University Hospital Bern

This study is for men whose prostate cancer has returned in the prostate bed after having their prostate removed. The treatment combines a short course of hormone therapy (6 months) with a high-dose, focused radiation therapy given in just 5 sessions. The goal is to see if this a…

This study tests whether adding extra ablation to the standard procedure helps people with persistent atrial fibrillation (a type of irregular heartbeat). About 206 adults with this condition will receive either standard vein isolation or that plus posterior wall ablation using a…

This study compares two procedures for treating a common heart rhythm problem called atrial fibrillation (AF). It involves 210 people with AF that comes and goes. One group gets the standard treatment using a freezing balloon, and the other gets a newer method using electrical pu…

This study compares a new leadless pacemaker (Micra AV) to a standard dual-chamber pacemaker in 100 older adults with heart block. The goal is to see if the leadless version works as well for exercise capacity. Both devices control heart rhythm, but the leadless one avoids wires …

This study is observing 4,500 people who need pacemakers or similar heart devices. The goal is to create a tool that predicts who is at risk of developing a weakened heart from the device itself. By identifying high-risk patients early, doctors can choose better pacing methods to…

This study looks at how bacteria from the gut might travel to surgical wounds and cause infections after abdominal surgery. Researchers collected samples from 209 patients before, during, and after surgery to track bacterial movement. The goal is to understand the process better,…

This study looks at how blood flow to the urethra relates to bladder pressure in people with and without stress urinary incontinence (leaking urine when coughing or sneezing). Researchers will use advanced ultrasound imaging in 70 adults to measure blood supply and compare it to …

This study looks at whether a tool called the Chelsea Critical Care Physical Assessment tool (CPAx) can accurately track recovery in 120 adults who developed muscle weakness after being on a breathing machine in the ICU. The goal is to find the smallest meaningful improvement tha…

This study looks at how a common heart valve procedure called TAVI changes the gut microbiome in older adults with aortic stenosis. Researchers will collect blood and stool samples before and three months after TAVI to measure bacterial byproducts and diversity. The goal is to se…

This study looks at whether adults aged 70 and older with multiple chronic conditions (but no heart disease) can safely stop taking statins. Researchers are comparing those who continue statins to those who stop, tracking deaths and major heart events over 2-4 years. The goal is …

This study compares how well doctors can measure tissue firmness using their hands (palpation) versus ultrasound. About 40 medical professionals and students will test artificial tissue models. The goal is to see which method is more accurate and reliable, and whether practice im…

This study looks at how the bacteria in your gut change during abdominal surgery and whether those changes can lead to infections at the surgery site. Researchers will collect samples from 120 adults having planned abdominal surgery to track these bacteria. The goal is to better …

This study looks at 1226 people having surgery at a Swiss hospital to find out if changes in the body's chemistry can predict infections like surgical site infections. Researchers collect blood, urine, and stool samples before and after surgery to search for early warning signs. …

This study tests a simple computer alert that reminds doctors to re-evaluate antibiotics after 72 hours. It involves 58 hospital wards and aims to reduce unnecessary antibiotic use. The goal is to improve patient care and fight antibiotic resistance.

This study tests two different ways doctors can create an emergency airway in infants when standard methods fail. Using a realistic rabbit model with simulated bleeding, 30 pediatric specialists will try both a surgical cut-down technique and a needle-guided technique. The goal i…