New short radiation course aims to stop returning prostate cancer
NCT ID NCT05746806
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial is testing a new way to treat prostate cancer that returns after the prostate has been removed. It combines a very short course of highly targeted radiation (just 5 sessions) with 6 months of hormone therapy. The goal is to see if this approach can control the cancer with fewer side effects than standard treatments. The study involves 36 men whose cancer has come back only in the prostate bed, as shown by advanced imaging.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ultrahypofractionated salvage radiotherapy (targeted radiation in 5 sessions) plus short-term androgen deprivation therapy (hormone therapy for 6 months)
What this could lead to
If successful, this approach could offer a more precise, shorter treatment option for men whose prostate cancer returns after surgery, potentially delaying further progression.
What could go wrong
This is a small, early-phase trial with only 36 participants, so results may not apply to everyone. Side effects from radiation and hormone therapy, such as fatigue or urinary issues, are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Inselgruppe AG, Inselspital
Bern, 3010, Switzerland
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Istituto Oncologico della Svizzera Italiana-Ente Ospedaliero Cantonale (IOSI-EOC)
Bellinzona, 6500, Switzerland
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Kantonsspital Winterthur, Klinik für Radio-Onkologie
Winterthur, 8401, Switzerland
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Universitätsspital Basel
Basel, 4031, Switzerland
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Universitätsspital Zürich, Klinik für Radio-Onkologie
Zurich, 8091, Switzerland