Insel Gruppe Ag, University Hospital Bern

This study looked at 65 people with advanced head and neck cancer that had spread to lymph nodes. It compared two approaches: having surgery to remove affected lymph nodes before chemo-radiation, versus chemo-radiation alone. The goal was to see if upfront surgery could reduce tr…

This study tested whether giving a clot-dissolving drug called tenecteplase directly into the brain artery can improve blood flow in stroke patients whose initial mechanical clot removal was not fully successful. 156 adults with acute ischemic stroke from a large vessel blockage …

This study tested a structured plan to remove excess fluid early in patients with septic shock. 170 ICU patients were randomly assigned to either the fluid removal protocol or standard care. The goal was to see if the plan could safely reduce fluid buildup by day three, which mig…

This study looked at whether a newer type of deep brain stimulation (DBS) electrode, which can steer electrical signals more precisely, improves mood and movement in people with Parkinson's disease. 105 participants received the directional electrodes as part of their standard ca…

This study tested whether colchicine, a drug used for gout, can prevent new atrial fibrillation (irregular heartbeat) and the need for a permanent pacemaker in people undergoing a minimally invasive heart valve replacement (TAVI). About 200 patients with severe aortic stenosis to…

This study tested whether using a combination of pain medicines (multimodal anesthesia) before and during major surgery leads to better recovery and satisfaction compared to using opioids alone. 240 adults having major surgery took part. The goal was to see if the multimodal appr…

This study tested whether giving clonidine before electroconvulsive therapy (ECT) reduces the confusion and agitation that can happen afterward. ECT is a highly effective treatment for severe depression and bipolar disorder, but up to 65% of patients experience post-seizure delir…

This study used a special camera to measure how long natural fluorescent substances in the retina stay lit up after being excited by light. The goal was to see if these measurements can reveal areas of the retina under stress, like from poor blood flow. Nearly 900 healthy volunte…

This study looked at whether people with cystic fibrosis (CF) develop antibodies after COVID-19 infection or vaccination. Researchers followed 5 participants for 2 years, taking blood samples and tracking lung health. The goal was to understand how CF affects COVID-19 risk and im…

This study looked at how children's lungs change during anesthesia for MRI scans. Researchers used a special imaging tool to measure poorly ventilated areas in the lungs of 30 children aged 1 to 6. The goal was to better understand these changes and improve safety in pediatric an…

This study looked at how being at high altitude (above 3000 meters) affects the performance of highly trained medical rescuers. Twenty experienced doctors performed simulated rescue scenarios at both low and high altitude. The researchers measured the quality of patient care usin…

This study tested a new Swiss German language test for children aged 4 to 6 with normal hearing. The goal was to measure how well kids understand words in quiet and noisy settings. The results will help doctors better assess hearing in Swiss German-speaking children.

This study tested whether healthy adults can learn to increase communication between brain regions using real-time feedback of their own brain activity (neurofeedback). The goal was to see if this heightened brain network activity could improve visual perception and motor learnin…

This study examined tumor budding—tiny clusters of cancer cells—in biopsy samples from 150 colorectal cancer patients. Researchers used a special stain to count these buds and then applied a mathematical model to predict whether the cancer had spread to lymph nodes or other organ…