Old drug, new trick: colchicine may cut heart complications after valve surgery

NCT ID NCT04870424

First seen Jun 05, 2026 · Last updated Jun 09, 2026 · Updated 2 times

Summary

This study tested whether colchicine, a drug used for gout, can prevent new atrial fibrillation (irregular heartbeat) and the need for a permanent pacemaker in people undergoing a minimally invasive heart valve replacement (TAVI). About 200 patients with severe aortic stenosis took either colchicine or a placebo for 30 days after the procedure. The goal was to see if the drug's anti-inflammatory effects could reduce these common post-surgery complications.

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Contacts and locations

Locations

  • Inselspital, Bern University Hospital, Department of Cardiology

    Bern, 3010, Switzerland

Conditions

Explore the condition pages connected to this study.