Hospital For Special Surgery, New York
Clinical trials sponsored by Hospital For Special Surgery, New York, explained in plain language.
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New spinal graft aims to heal backs better
Disease control ENROLLING_BY_INVITATIONThis study is looking at how well a new bone graft material called Natural Matrix Protein (NMP) works for people having surgery to fuse their lower spine. It will follow about 100 adults with severe back pain who have already had this specific surgery. Researchers will check X-ra…
Sponsor: Hospital for Special Surgery, New York • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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First human test: can cord cells fix torn shoulders?
Disease control ENROLLING_BY_INVITATIONThis early-stage study is testing whether adding special lab-grown cells from umbilical cords to standard shoulder surgery is safe and might improve healing. The trial will enroll 20 adults aged 45-70 with full-thickness rotator cuff tears who haven't improved with physical thera…
Phase: PHASE1 • Sponsor: Hospital for Special Surgery, New York • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Surgery vs. therapy: the race to stop young knees from popping out
Disease control ENROLLING_BY_INVITATIONThis study aims to find the best way to prevent repeat kneecap dislocations in patients aged 25 and younger. It compares two approaches: surgery to reconstruct a key knee ligament versus a non-surgical program of physical therapy. Researchers will follow 240 participants for five…
Phase: NA • Sponsor: Hospital for Special Surgery, New York • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Fat cells could be key to fixing torn shoulders
Disease control OngoingThis study is testing whether a patient's own fat cells can help heal a torn rotator cuff tendon. Doctors will collect fat from the patient's abdomen during surgery, process it to get special healing cells, and inject them into the repaired shoulder. The goal is to see if these c…
Phase: PHASE2 • Sponsor: Hospital for Special Surgery, New York • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Could a simple Pre-Surgery check spot hidden health danger?
Diagnosis TerminatedThis study aimed to see if checking blood pressure before outpatient surgery could help find people with undiagnosed high blood pressure. It planned to enroll adults having elective surgery who had high readings but no prior diagnosis. Researchers would then follow up to see if t…
Sponsor: Hospital for Special Surgery, New York • Aim: Diagnosis
Last updated Mar 30, 2026 14:34 UTC
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Could a simple At-Home quiz help diagnose a debilitating pain disorder?
Diagnosis ENROLLING_BY_INVITATIONThis study aims to validate a new self-report questionnaire designed to help diagnose Complex Regional Pain Syndrome (CRPS) remotely. Researchers will compare the new patient-completed survey against the current standard, which requires an in-person doctor's exam. The goal is to …
Sponsor: Hospital for Special Surgery, New York • Aim: Diagnosis
Last updated Mar 20, 2026 14:48 UTC
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Can a simple walking plan get back surgery patients moving again?
Symptom relief OngoingThis study tests a program designed to help people walk more after recovering from low back surgery. It involves 260 patients who had surgery for degenerative spine conditions. The goal is to see if a structured walking program, starting a few months after surgery, can safely inc…
Phase: NA • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Could a common pill be the key to beating tennis elbow?
Symptom relief OngoingThis study is checking if a very low dose of the antibiotic doxycycline is a practical addition to standard home exercises for treating persistent elbow tendon pain (like tennis elbow). It will see if patients are willing to try it and stick with the treatment plan. The goal is t…
Phase: PHASE1 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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New hope for debilitating pain? study tests repurposed drug
Symptom relief ENROLLING_BY_INVITATIONThis study is exploring if a very low dose of an existing medication, naltrexone (called LDN), can help manage the severe pain and other symptoms of Complex Regional Pain Syndrome (CRPS). Over six months, 40 participants will take either LDN or a placebo (inactive pill) daily to …
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Could a multiple sclerosis drug help people with PLS walk better?
Symptom relief OngoingThis study is testing whether a drug called dalfampridine, which is used to improve walking in multiple sclerosis, is safe and might help people with primary lateral sclerosis (PLS) walk faster and improve their daily function. Over 18 weeks, 35 participants with PLS will take th…
Phase: PHASE1 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Shockwave showdown: which therapy zaps heel pain best?
Symptom relief OngoingThis study compares two non-surgical shockwave treatments for chronic heel pain from plantar fasciitis. It involves 114 adults with long-lasting pain that hasn't improved with other treatments. Researchers are testing whether radial or focused shockwave therapy provides better pa…
Phase: NA • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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New back surgery anesthesia study aims to reduce pain and opioid use
Symptom relief ENROLLING_BY_INVITATIONThis study is comparing two different anesthesia approaches for common back surgeries like microdiscectomy. Researchers want to see if using spinal anesthesia with a nerve block leads to better recovery, less pain, and less need for opioid painkillers after surgery compared to th…
Phase: PHASE3 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Can a simple shot unlock stiff knees after surgery?
Symptom relief OngoingThis study is testing if giving an intravenous steroid (hydrocortisone) right after a total knee replacement helps patients bend and straighten their knee better later on. It involves 132 patients who will be randomly assigned to receive either the steroid or a placebo (saltwater…
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Fat solution tested to wake up numb legs faster
Symptom relief OngoingThis study is testing if a common fat solution called Intralipid, given through an IV, can make numbness from local anesthetics wear off faster. Researchers are enrolling 18 healthy volunteers to receive small injections of numbing medicine in their thigh, followed by either the …
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Mar 23, 2026 15:18 UTC
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Can a Heat-Sensing camera see your pain?
Knowledge-focused OngoingThis study is testing whether a special thermal camera can help doctors measure pain severity in people newly diagnosed with Complex Regional Pain Syndrome (CRPS). Researchers will take heat pictures of participants' feet and compare them to standard pain questionnaires. The goal…
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Why do some patients take longer to wake up after surgery?
Knowledge-focused OngoingThis study aims to understand why some patients take longer than expected to be ready to go home after outpatient foot and ankle surgery. Researchers will review the medical records of 1,000 adult patients to identify common reasons for these delays. The goal is to find factors t…
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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Massive study aims to unlock secrets of lasting knee replacements
Knowledge-focused OngoingThis study is gathering long-term information from 3,000 people who get knee replacements at a major hospital. It aims to track how well the new knees work, how long they last, and what factors lead to the best results over many years. Unlike most research that only follows patie…
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC
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Do patients and surgeons agree on what back surgery will achieve?
Knowledge-focused OngoingThis study examines whether patients and their surgeons have similar expectations about what lumbar spine surgery will accomplish. Researchers surveyed 437 patients scheduled for back surgery and their surgeons before the procedures to compare their expectations about physical an…
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:22 UTC