Hospital For Special Surgery, New York

This study tests whether a daily injection of abaloparatide, a drug that strengthens bones, can improve healing after spinal fusion surgery. About 96 postmenopausal women and men with low bone mass will receive either the drug or a placebo for 6 months. Researchers will check bon…

This study tests whether using a patient's own fat cells (called stromal vascular fraction) during rotator cuff surgery can improve healing. 56 adults aged 45-65 with chronic tears are enrolled. The cells are collected from belly fat during surgery and injected into the torn tend…

This study looks at a new material called Natural Matrix Protein (NMP) used in spine fusion surgery for people with worn-out discs in their lower back. About 100 adults who have not gotten better with other treatments will be followed for a year to see if the NMP helps bones fuse…

This study looks at whether surgery to repair a ligament in the knee (MPFL reconstruction) is better than non-surgical treatment for preventing repeat kneecap dislocations in people aged 25 and younger who have dislocated their kneecap once. About 240 participants will be followe…

This early-stage trial tests whether adding special cells (E-CEL UVEC) to standard rotator cuff surgery is safe and possible. About 20 adults aged 45-70 with full-thickness tears will receive the cells at the repair site. The main goal is to check for short-term side effects, not…

This study aims to validate a new self-report questionnaire that people with Complex Regional Pain Syndrome (CRPS) can fill out at home to measure their symptom severity. Researchers will compare the self-report results with in-person clinical exams to see if the questionnaire is…

This study tests whether a very low dose of naltrexone, a drug usually used for addiction, can help reduce pain and other symptoms in people with Complex Regional Pain Syndrome (CRPS). Forty adults with severe CRPS pain will receive either the drug or a placebo for six months. Th…

This study compares two types of shockwave therapy (radial vs. focused) to see which better reduces morning pain and pain after walking or standing in people with chronic plantar fasciitis. 114 adults with heel pain lasting over 3 months that hasn't improved with other treatments…

This study looks at two ways to numb people for lower back surgery. One group gets standard general anesthesia (fully asleep) plus a nerve block, and the other gets spinal anesthesia (awake but numb from the waist down) plus a nerve block. The goal is to see which approach helps …

This early-stage trial tests whether dalfampridine, a drug used for walking problems in multiple sclerosis, can safely improve walking speed in 35 adults with primary lateral sclerosis or a related upper motor neuron condition. Participants take the drug for 18 weeks and have the…

This study tests a program to help people increase their walking after lumbar spine surgery. Many patients avoid activity due to fear of pain or injury, so the program starts several months after surgery. Researchers will measure changes in weekly walking and pain-related disabil…

This study looks at whether giving the steroid hydrocortisone through a vein can improve how much people can bend and straighten their new knee after total knee replacement surgery. About 132 adults with knee arthritis who are having their first knee replacement will take part. S…

This study follows 3000 people who had hip replacement surgery at Hospital for Special Surgery. Researchers want to learn how well the new hips work over many years, how patients' quality of life changes, and which factors predict success or failure. Participants simply fill out …

This study looks back at the records of 1000 adults who had foot/ankle surgery to understand what causes delays in leaving the recovery room. Researchers will measure how long patients stay and how much pain medication they need. The goal is to find ways to make recovery faster a…

This study follows 3,000 people who have had knee replacement surgery at Hospital for Special Surgery. Researchers want to learn how well the new knees work over many years, including pain relief and how long the implants last. Participants only fill out questionnaires; no new tr…

This study compares what patients and their surgeons expect from lumbar spine surgery. Researchers want to see if they agree on the likely outcomes. About 437 adults scheduled for non-emergency spine surgery will fill out surveys. No new treatment is tested; the goal is to improv…

This study planned to check if notifying ambulatory surgery patients with undiagnosed high blood pressure would help them get a formal diagnosis. Researchers would call patients with elevated readings (over 160/90) and follow up after 6 months. However, the study was withdrawn be…

This study tests whether Intralipid 20%, a fat emulsion, can reverse the numbing effect of local anesthetics faster than a saltwater solution. Eighteen healthy volunteers receive small injections of numbing medicine in their thighs and then get either Intralipid or saline. Resear…