Can a steroid help your new knee bend better?
NCT ID NCT04082533
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the steroid hydrocortisone can improve knee movement after total knee replacement. About 132 patients, some with naturally stiff knees, will receive either the drug or a placebo right after surgery. Researchers will measure how well the knee bends and straightens at 6 weeks, and follow up for 2 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hydrocortisone
- What this could lead to
- If it works, this could point toward a simple way to reduce stiffness and improve knee movement after replacement surgery.
- What could go wrong
- This is a small, early-phase trial. The drug may not improve range of motion more than placebo, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital for Special Surgery
New York, New York, 10021, United States
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