Hospital Clinic Of Barcelona

This study compares a newer pacing method (conduction system pacing) with standard biventricular pacing in 320 adults with heart failure and wide QRS. The goal is to see which method better reduces the risk of death, need for a heart transplant, or hospitalization for heart failu…

This study compares two procedures—pulsed field ablation and cryoballoon ablation—for treating atrial fibrillation, a common heart rhythm problem. About 104 people having their first ablation will be randomly assigned to one method. The goal is to see which technique creates bett…

This study looks at 48 people who need a pacemaker after a TAVI procedure (a less invasive heart valve replacement). Researchers want to see if a newer 'physiological' pacing method helps people feel better and walk farther compared to standard right ventricular pacing. Participa…

This study tests if a newer, more natural pacing method can prevent the heart from weakening after pacemaker implantation. Researchers will compare it to standard pacing in 200 adults who need a pacemaker for a slow heartbeat. The goal is to see which method better avoids heart f…

This study compares two surgical techniques for creating arteriovenous fistulas (AVFs) needed for hemodialysis in people with advanced chronic kidney disease. The standard end-to-side method is being tested against a newer piggyback technique that may reduce complications like na…

This pilot study tests a personalized approach to treat atrial fibrillation (AF), a common heart rhythm problem. Instead of the standard procedure, doctors will use a special noninvasive mapping system to identify and target the exact areas causing the abnormal rhythm in each pat…

This study tests whether a program of physical exercise, nutritional guidance, and psychological support during chemotherapy can improve how well breast cancer responds to treatment. About 214 women with early-stage breast cancer will be randomly assigned to either receive this e…

This study tests whether a non-drug program combining physical exercise, nutritional guidance, and psychological support can reduce severe fatigue in people with primary biliary cholangitis (PBC). Researchers will enroll 64 adults with PBC and moderate-to-severe fatigue. The goal…

This study tests whether different types of electrical nerve stimulation can improve leg strength in athletes with patellar tendinopathy (jumper's knee). Nineteen athletes will receive three different stimulation methods in separate sessions. The goal is to see which frequency wo…

This study tests whether high-flow nasal oxygen (HFNO) can prevent low oxygen levels and breathing complications in patients undergoing a less invasive heart valve replacement called TAVR. About 452 adults having elective TAVR will receive either HFNO or standard oxygen during se…

This study tests a therapy called m-CIMT for people who recently had a stroke and have arm weakness. The treatment involves restricting the unaffected arm and doing specific exercises with the affected arm to improve its use and function. Researchers will measure changes in arm m…

This study looks at whether using a CPAP machine at night can improve asthma control in adults with both severe, hard-to-control asthma and obstructive sleep apnea. About 138 participants will use CPAP and be monitored for changes in asthma symptoms and lung function. The goal is…

This study looks at whether adjusting the settings on a mechanical cough-assist device (MI-E) can remove more mucus from the lungs of critically ill patients on breathing machines. About 26 adults who have been on a ventilator for more than 48 hours will take part. Researchers wi…