Hackensack Meridian Health

This study looks at whether a cardiac rehabilitation program can improve recovery for people who have had a stroke. Researchers will enroll 150 stroke survivors and add cardiac rehab to their usual care. They will measure walking ability, daily function, and whether the program r…

This study tests whether a specific combination of chemotherapy (fludarabine), radiation, and a drug called cyclophosphamide can improve survival one year after a stem cell transplant for blood cancers. About 209 adults aged 18-65 with certain leukemias or related disorders will …

This study tests whether a clinic that provides extra education, tools, and follow-up calls can reduce hospital readmissions for people with a type of heart failure called HFpEF. About 150 adults discharged from Ocean University Medical Center will either receive this extra suppo…

This early-phase study tests a drug called carfilzomib combined with standard chemotherapy to see if it helps collect more stem cells for transplant in people with multiple myeloma. The main goals are to find the safest dose and check for side effects. About 18 participants will …

This study tests a mistletoe extract (Iscador P) in 32 patients whose osteosarcoma has returned in the lungs and has been surgically removed. The goal is to see if the treatment can delay or prevent the cancer from coming back. Participants receive injections of the extract and a…

This study tests a combination of three drugs (carfilzomib, iberdomide, and dexamethasone) in people newly diagnosed with multiple myeloma who are eligible for a stem cell transplant. The goal is to see if this treatment is safe and effective at reducing cancer before transplant.…

This study tests whether a single dose of a radioactive drug (Lu-177-PSMA-617) given before surgery can shrink or eliminate high-risk prostate cancer. About 54 men with aggressive prostate cancer will receive the drug, then have their prostate removed. The goal is to see if the d…

This study looks at whether a simple blood test that tracks tumor DNA can help doctors decide if patients with advanced lung cancer can be treated with immunotherapy alone or need chemotherapy added. About 108 adults with newly diagnosed stage IV non-small cell lung cancer will p…

This study looks at whether a PSMA-PET scan can spot prostate cancer that comes back after a type of treatment called focal therapy. About 70 men who had focal therapy for intermediate-risk prostate cancer will get a PSMA-PET scan one year later. The scan results will be compared…

This study tests whether taking Flomax (tamsulosin) daily for a week before chest surgery can prevent urinary retention—a common problem where men can't urinate after the operation. About 127 men aged 50 and older having minimally invasive chest surgery will participate. The goal…

This study compares two remote training programs to see which better helps people with mild traumatic brain injury (concussion) improve their emotional health and well-being. It involves 300 adults who are at least 6 months post-injury and have trouble identifying or managing emo…

This study looks at whether a lower dose (15mg) of the painkiller ketorolac works as well as a higher dose (30mg) for kidney stone pain in the emergency department. About 86 adults with severe pain will receive one of the two doses, and their pain levels will be tracked over seve…

This study compares two types of talk therapy—cognitive behavioral therapy (CBT) and interpersonal therapy (IPT)—for mothers of NICU babies who have postpartum depression. It will test if a 4-week course of one therapy works better than the other, and if combining both over 8 wee…

This early-phase study tests whether Tamsulosin, a drug often used for prostate problems, can help men aged 55 and older urinate on their own after surgery for suspected or confirmed lung cancer. About 46 men will take the drug before and after their operation. The goal is to see…

This study tests a stress management program for people with lung cancer who feel anxious while waiting for routine scan results. About 60 adults will try coaching sessions and online modules to learn relaxation skills. The goal is to see if the program is helpful and easy to use…

This study looks at whether a lung ultrasound done shortly after birth can predict which late preterm babies (born 34–36 weeks) will have breathing problems in the first two days of life. Researchers will compare three different ultrasound scoring methods in 300 newborns. The goa…

This study creates a worldwide registry for children diagnosed with Embryonal Tumor with Multilayer Rosettes (ETMR), a rare and aggressive brain tumor. Researchers will collect medical records, tumor tissue, and treatment outcomes from up to 100 patients of any age. The goal is t…

This study tests a new way to increase lung cancer screening in people at high risk. Researchers will use the emergency department to identify eligible patients and offer them extra help to get a low-dose CT scan. The goal is to see if this approach works better than standard car…

This study aims to better understand cancer risk and improve screening by collecting health information from 10,000 adults who have a higher chance of developing cancer. Participants will fill out questionnaires and may have genetic testing to find inherited risks. The goal is to…