Hackensack Meridian Health

This study tested the drug carfilzomib in 7 people with Waldenström's macroglobulinemia, a rare blood cancer, that had returned after previous treatment. The goal was to see if the drug could shrink tumors and control the cancer. Carfilzomib works by blocking a protein that helps…

This study tested whether adding a drug called vorinostat to standard therapy (lenalidomide and dexamethasone) could help patients with multiple myeloma whose cancer had stopped responding to lenalidomide. The trial enrolled 25 adults with relapsed or refractory multiple myeloma.…

This study tested a two-step treatment for multiple myeloma, a blood cancer. Patients received high-dose chemotherapy followed by a stem cell transplant, then a second round with an added drug. The goal was to see if this approach could keep the cancer from coming back longer. 14…

This study tested adding thalidomide to two other chemotherapy drugs (bortezomib and melphalan) before a stem cell transplant in 29 people with advanced multiple myeloma who had already tried a similar transplant. The goal was to find the safest dose of thalidomide and see if the…

This study tested adding lenalidomide to a standard chemotherapy regimen (RICE) for people with diffuse large B-cell lymphoma that had come back after initial treatment. The goal was to see if the combination could shrink tumors more effectively, allowing more patients to proceed…

This early study tested a new treatment called Stem Cell Educator therapy in 13 adults with type 1 diabetes. The goal was to see if it is safe and possible to do. The treatment uses a device to 'educate' the patient's own immune cells outside the body, then returns them, aiming t…

This study tested a treatment for people with previously untreated chronic lymphocytic leukemia (CLL). Participants received a combination of chemotherapy drugs (fludarabine, cyclophosphamide, rituximab) plus lenalidomide, followed by lenalidomide alone to keep the disease under …

This study tested a stem cell transplant using a three-drug conditioning regimen (fludarabine, melphalan, and bortezomib) in 54 adults with multiple myeloma. The goal was to see if this combination improved how long patients lived without the cancer getting worse, compared to usi…

This study tested a special pad (PadKit™) worn for 4-6 hours to collect cells shed from the uterus. Researchers checked if the pad could tell normal cells from abnormal or cancerous ones. 80 women scheduled for surgery took part. The goal was to see if this comfortable, at-home m…

This study tested a smartphone app that analyzes voice recordings to see if it can accurately diagnose mild cognitive impairment (MCI) and Alzheimer's disease. Researchers compared the app's diagnosis to a doctor's diagnosis in 150 adults aged 50 and older. The goal was to see if…

This study tested whether helping people with social needs (like housing or food) increases lung cancer screening rates. 101 adults aged 50-80 who smoke or quit recently took part. One group got a screening education tool alone; the other also got help connecting to social servic…

This study tested whether Facebook ads and a tailored online tool called LungTalk could help people at high risk for lung cancer learn more about screening. Over 500 current or former heavy smokers participated. The goal was to see if social media can effectively reach and educat…

This study looked at 49 people with triple negative breast cancer to see if the bacteria in their gut and tumors influenced how well chemotherapy worked. Researchers collected samples before and during treatment to find links between certain bacteria and a complete response. The …