Guy's And St Thomas' Nhs Foundation Trust

This study tested a new type of breathing machine that automatically adjusts its settings to match each person's breathing in real time. Fifteen people with severe COPD who already use a ventilator at home tried the device for six weeks. The goal was to see if the smart ventilato…

This study looked at whether a new blood test (NuQ H3.1) can help doctors diagnose sepsis faster in adults admitted to intensive care with signs of infection. Researchers compared 34 sepsis patients to a group of surgical patients without infection. The goal was to see if the tes…

This trial tests whether a shorter-acting spinal anesthetic (prilocaine) helps pregnant women recover feeling and movement faster after a cervical stitch procedure compared to the standard drug (bupivacaine). About 129 healthy pregnant women at risk of preterm loss will receive o…

This study looks at how often children develop low blood sugar (hypoglycemia) after fasting before anesthesia for elective procedures. Researchers will monitor blood sugar levels in over 6,500 children aged 1 month to 18 years to find a clear definition of hypoglycemia and identi…

This observational study looks at why some people with severe asthma continue to have flare-ups even while taking tezepelumab, an approved treatment. Researchers will track 150 patients over a year, measuring changes in inflammatory cells and markers in blood and airways during a…

This study looked at whether patients who had heart surgery can safely and effectively collect swabs from their own chest wounds at home. 43 adults were observed via video call as they swabbed themselves, then sent the samples to a lab. The goal was to see if this method is accep…

This study looked at whether the groove between the buttocks (intergluteal cleft) can help doctors find the midline of the spine in pregnant women, compared to using ultrasound. 100 women at 37+ weeks of pregnancy were included. The goal was to see how far this landmark is from t…

This study looked at how a stay in intensive care affects a person's ability to drive safely. It involved 40 adults who had been on a breathing machine for at least 3 days. Researchers used a driving assessment to find out what difficulties people face and whether the test is pra…