Guy's And St Thomas' Nhs Foundation Trust
Clinical trials sponsored by Guy's And St Thomas' Nhs Foundation Trust, explained in plain language.
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Could a vibrating mesh nebuliser ease breathing for COPD patients on ventilation?
Disease control OngoingThis study tests whether a vibrating mesh nebuliser delivers bronchodilator medication more effectively than a standard jet nebuliser in people with COPD who use non-invasive ventilation at home. Researchers will measure breathing muscle activity, lung function, and breathlessnes…
Phase: NA • Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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NHS digital tool aims to tackle obesity epidemic
Disease control ENROLLING_BY_INVITATIONThis study is testing a new digital weight management program for adults with obesity who are referred to NHS Tier 3 services. The program uses a smartphone app to help people manage their weight. Researchers want to see if it improves health, saves money, and works well for pati…
Phase: NA • Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Heart pump may protect patients during risky stent procedures
Disease control OngoingThis study tests whether a temporary heart pump can help high-risk patients during coronary stenting. The pump supports the heart's main chamber during the procedure, aiming to prevent heart failure or death. About 300 patients with severe coronary disease and weak heart muscle w…
Phase: PHASE3 • Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Could a vibrating mesh nebuliser help clear airways in Long-Term tracheostomy patients?
Symptom relief OngoingThis pilot study tests whether a vibrating mesh nebuliser works better than a standard jet nebuliser for people who need long-term breathing support through a tube in their windpipe (tracheostomy). The trial will measure how well the lungs work, how easily mucus is cleared, and h…
Phase: NA • Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Symptom relief
Last updated Jul 15, 2026 00:00 UTC
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New scan method could prevent unnecessary stents after heart attacks
Knowledge-focused OngoingThis study looks at 90 people who recently had a heart attack and have other artery narrowings that may or may not be dangerous. Researchers will use two types of scans—optical coherence tomography (OCT) and magnetic resonance angiography (MRA)—to see if they can tell which narro…
Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC