Fondazione I.r.c.c.s. Istituto Neurologico Carlo Besta

This study compares Botox injections guided by ultrasound versus standard injections (using body landmarks) for people with cervical dystonia, a condition causing neck muscle spasms and pain. About 100 adults will receive both types of injections at different times to see which i…

This study looks for biological markers (biosignatures) in people with ALS and FTD to make diagnosis more accurate. Researchers will analyze samples like spinal fluid, skin, and tears from 230 participants using advanced methods. The goal is to create a disease fingerprint that h…

This study looks at how deep brain stimulation (DBS) affects brain networks in people with dystonia, a movement disorder. Researchers will use brain scans and electrical recordings from 15 participants who already have DBS implants. The goal is to understand how DBS changes brain…

This study looks at whether using lower doses of sedation during brain tumor surgery helps patients wake up more quickly and safely after anesthesia. Researchers will track 100 adults having elective neurosurgery and measure how the amount of anesthetic affects their recovery. Th…

This study creates a network of hospitals across Italy to better understand and diagnose rare cerebrovascular diseases (rCVDs) like CADASIL, Fabry disease, and Moyamoya. Researchers will collect health information from 500 patients to describe the diseases' features and natural h…

This study looks at how attention and vision problems change over time in 40 adults with a glioma in the parietal lobe of the brain. Participants will complete thinking and vision tests before and after surgery. The goal is to better understand these deficits so doctors can creat…

This study explores whether ultrasound, a low-cost and widely available tool, can help doctors better understand and treat people with disorders of consciousness, such as coma or a minimally conscious state. Researchers will use brain ultrasound to measure brain activity and trac…

This study aims to standardize care for people with rare brain tumors by using artificial intelligence to analyze patient data. Researchers will collect information from 200 adults before and after surgery, including symptoms, cognitive function, and quality of life. Participants…

This study looks for new ways to detect and track ALS earlier by studying nerve tissue and blood from 400 people with ALS or at risk. Researchers will use advanced techniques to find molecular changes that signal the start or progression of the disease. The goal is to develop rel…