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Sound waves vs. dystonia: could a No-Cut brain treatment end limb twisting?

NCT ID NCT07168850

Recruiting now Disease control Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a non-invasive procedure called focused ultrasound for adults with limb dystonia that hasn't improved with medication or Botox. The treatment uses sound waves to create a tiny lesion in a brain area that controls movement. Researchers will compare real treatment to a sham procedure to see if it safely reduces symptoms and improves quality of life.

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Conditions

The condition(s) this trial relates to.

Dystonia dystonic disorder early-onset generalized limb-onset dystonia focal dystonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DYSTONIA, FOCAL IDIOPATHIC DYSTONIA LIMB DYSTONIA MEDICATION-REFRACTORY DYSTONIA

Contacts and locations

Locations

  • Azienda Ospedaliera Ospedali Riuniti Villa Sofia

    RECRUITING

    Palermo, 90146, Italy

  • Azienda ULSS3 Serenissima

    RECRUITING

    Mestre, (Venice), 30174, Italy

  • Fondazione IRCCS Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, 20133, Italy

  • IRCCS Centro Neurolesi "Bonino-Pulejo"

    RECRUITING

    Messina, 98124, Italy

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