Fondazione I.r.c.c.s. Istituto Neurologico Carlo Besta

This study tested a personalized immunotherapy for people with newly diagnosed glioblastoma, an aggressive brain cancer. Patients received injections of their own immune cells (dendritic cells) trained to attack their tumor. The goal was to see if this treatment is safe and could…

This study tested a new way to deliver radiation (hypofractionated stereotactic radiotherapy) to people with non-secreting pituitary tumors that remained or came back after other treatments. The goal was to see if this method could control tumor growth while reducing side effects…

This study tested whether adding Acceptance and Commitment Therapy (ACT) to standard migraine drugs could reduce monthly headache days in people with frequent migraines (9-14 days per month). 64 adults were split into two groups: one received only medication, the other added 6 we…

This study followed 200 adults with cerebral amyloid angiopathy (CAA), a condition where protein builds up in brain blood vessels, raising the risk of bleeding and memory problems. Researchers used brain scans, spinal fluid, and blood tests to track how the disease changes over t…

This study looked at 160 adults having planned brain surgery to see if raising blood pressure during the operation makes it harder for surgeons to stop bleeding. Doctors increased blood pressure slightly with a medicine and noted if extra steps were needed to control bleeding. Th…

This observational study looked at whether the brain's waste-clearing system (glymphatic system) is impaired in people with normal pressure hydrocephalus (NPH). Researchers used a special MRI technique called DTI-ALPS in 29 patients and a healthy control group. The goal was to se…

This study looked at how common thinking and memory problems are in people with myasthenia gravis, and how these issues affect work, daily activities, and quality of life. Researchers studied 150 adults with MG to measure cognitive function and its links to disability, fatigue, a…