Glowing dye could help surgeons spot hidden brain tumor cells
NCT ID NCT07233954
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a dye called sodium fluorescein can help surgeons better see and remove aggressive brain tumors during surgery. The dye is injected into the bloodstream and collects in tumors where the blood-brain barrier is broken, making them glow under a special microscope. Researchers will enroll about 100 patients with suspected CNS tumors to see how well the dye works and if it leads to more complete tumor removal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sodium fluorescein
- What this could lead to
- If successful, this could help surgeons remove more tumor tissue during brain surgery, potentially improving survival and quality of life for patients with aggressive CNS tumors.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove the dye improves outcomes. Results may not apply to all patients, and there is a small risk of allergic reactions to the dye.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fondazione IRCCS Istituto Neurologico Carlo Besta
RECRUITINGMilan, Italy
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