First Affiliated Hospital Of Fujian Medical University

This study looks at whether adding the antibiotic rifampin to usual treatment can better clear staphylococcal infections in artificial joints. About 428 adults who had joint replacement surgery and developed an infection will take part. After surgery to clean the joint, they rece…

This study looks at whether adding a specific gut bacteria (Bacteroides fragilis) and branched-chain amino acids to standard hepatitis B treatment can help clear the virus. About 40 adults with chronic hepatitis B will take the combo alongside their usual antiviral drugs, and the…

This early-stage trial tests a new drug called 225Ac-LNC1011 in 9 men with a type of advanced prostate cancer that no longer responds to hormone therapy. The drug delivers radiation directly to cancer cells using a targeting molecule (PSMA). The main goals are to find the safest …

This study tests whether using a special scan (PSMA PET/MRI) to guide prostate biopsies can find more cancers than standard methods. It includes 230 men who have had a previous negative biopsy but still have signs of possible prostate cancer. The goal is to improve early detectio…

This study compares a special PET scan (68Ga-PSMA-11) with standard MRI to see which better detects prostate cancer in 100 newly diagnosed men who haven't had treatment yet. Participants will receive both scans before their scheduled prostate removal surgery, and results will be …

This study is testing a new radioactive tracer called 68Ga-P16-093 to see how well it finds prostate cancer using PET scans. It will compare the results to standard MRI scans in 50 people who have just been diagnosed but haven't started treatment yet. The goal is to see if this n…

This study tests two new imaging probes (68Ga-G21 and 68Ga-G23) that target a protein found on most prostate cancer cells. The goal is to see if these probes can detect and stage prostate cancer better than current scans, especially when standard PSMA PET scans are negative or un…

This study tests whether low-intensity focused ultrasound can safely improve motor symptoms in people with Huntington's disease. About 24 adults with genetically confirmed Huntington's will receive the ultrasound treatment. The goal is to find the best pulse frequency that reduce…

This study compares different doses of steroids given directly into the knee during total knee replacement surgery. The goal is to find the safest and most effective dose to reduce pain and improve recovery. About 120 adults having knee replacement will take part, and their pain,…

This study looks at how well three AI chatbots—ChatGPT, Gemini, and Deepseek—can diagnose and suggest treatments for urology diseases. Researchers will use 800 past patient records from four hospitals to check the AI's accuracy and usefulness. The goal is to see if these AI tools…

This study is creating a large database of 8,000 adults with heart, kidney, or metabolic diseases (like diabetes). Researchers will collect medical records, imaging, and lab results, then follow participants for up to 5 years. The goal is to better understand how these conditions…

This study is enrolling 20,000 adults in Taining County, China, to better understand common chronic diseases like high blood pressure, diabetes, and frailty. Researchers will collect health data and samples over three years to find patterns and risk factors. The goal is to create…