Targeted radiation zaps Hard-to-Treat prostate cancer in early trial

NCT ID NCT07363486

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new radioactive drug called 225Ac-LNC1011 in men with metastatic castration-resistant prostate cancer that has spread and stopped responding to hormone therapy. The drug targets a protein (PSMA) on cancer cells to deliver radiation directly. Nine participants will receive up to 4 doses to find the safest and most effective amount.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
225Ac-LNC1011 (a radioactive drug that targets prostate cancer cells)
What this could lead to
If it works, this could provide a new treatment option for men with advanced prostate cancer that has stopped responding to standard hormone therapy.
What could go wrong
This is a very early, small trial with only 9 participants, so results may not apply to everyone. The radioactive drug can cause side effects like fatigue, low blood counts, or damage to healthy organs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University

    RECRUITING

    Fuzhou, Fujian, 350005, China

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