Endeavor Health

This pilot trial tests whether using placental tissue analysis from a prior complicated pregnancy can guide treatment with the blood thinner enoxaparin to reduce the risk of recurrent adverse outcomes. The study enrolls women who had a previous pregnancy affected by early deliver…

This study tests whether a drug called IVIG (Panzyga) can help people with small fiber neuropathy, a condition causing nerve pain and damage. Researchers will give 20 adults either IVIG or a placebo for 6 months, then check nerve fiber growth in skin biopsies and pain levels. The…

This study tests whether an extra nerve block given during weight-loss surgery can lower pain, nausea, and the need for painkillers in the first three days after surgery. About 200 adults having gastric bypass or sleeve gastrectomy will be randomly assigned to get either standard…

This study tests whether personalized social activities—like group classes or events—can help adults aged 55 and older who feel lonely. Participants work with a coordinator to choose activities they enjoy and aim to do at least 2 hours per week for 6 months. Researchers track cha…

This study tests whether taking zinc supplements before a Botox injection can improve results for women with overactive bladder. 72 women will receive either zinc or a placebo pill for five days before their Botox treatment. Researchers will track how many need another injection …

This observational study investigates whether prenatal ultrasound can predict placental abnormalities found after delivery. Researchers will compare imaging features from 320 pregnancies with and without placental pathology. The goal is to improve detection of placental issues th…

This study tests TeamBirth, a program where labor and delivery teams hold short huddles with patients to make decisions together. Researchers want to see if this approach lowers the rate of first-time C-sections, especially for Black birthing people, and improves how patients fee…

This study is testing whether a non-invasive nerve monitoring device called TetraGraph can accurately detect early signs of ICU-acquired weakness. Researchers will compare readings from the device with standard needle-based electromyography (EMG) tests in healthy volunteers and I…

This study will use a special type of MRI (fMRI) to measure blood flow and oxygen levels in the placenta during the second and third trimesters of pregnancy. Researchers want to see if these measurements differ between women who were obese before pregnancy and those with a normal…

This study looks at whether a person's inherited genetic risk can predict if they have prostate cancer. Researchers will compare the genetic risk scores of 1,000 men aged 40-69 who are already scheduled for a prostate biopsy. The goal is to see if men with higher genetic risk are…

This study tests whether adding trained peer counselors who have breastfed themselves can help Black and Hispanic families breastfeed longer and more exclusively. About 990 pregnant people will be enrolled. The goal is to reduce known disparities in breastfeeding rates.