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Could a simple patch replace painful needle tests for ICU muscle weakness?

NCT ID NCT07699562

Recruiting now Knowledge-focused Sponsor: Endeavor Health Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study is testing whether a non-invasive nerve monitoring device called TetraGraph can accurately detect early signs of ICU-acquired weakness. Researchers will compare readings from the device with standard needle-based electromyography (EMG) tests in healthy volunteers and ICU patients, both on and off ventilators. The goal is to see if the non-invasive method can reliably track muscle response signals in the hand and leg over about 10 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
TetraGraph (non-invasive nerve monitoring device)
What this could lead to
If the TetraGraph proves accurate, it could offer a simpler, less painful way to detect muscle weakness early in ICU patients, potentially improving outcomes.
What could go wrong
This is a small, early-stage study with only 24 participants. The device may not match the accuracy of standard invasive tests, and results may not apply to all ICU patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

critical illness polyneuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ICU ACQUIRED WEAKNESS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Endeavor Health

    RECRUITING

    Evanston, Illinois, 60201, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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