Endeavor Health
Clinical trials sponsored by Endeavor Health, explained in plain language.
-
Could IV tylenol replace opioids after brain surgery?
Symptom relief CompletedThis study tested whether giving intravenous acetaminophen (Tylenol) during and after brain surgery could reduce the need for opioid painkillers. 140 adults having open brain surgery were randomly assigned to receive either IV Tylenol or a placebo. The main goal was to see if mor…
Phase: PHASE4 • Sponsor: Endeavor Health • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
-
New anesthesia combo could slash opioid use after hernia surgery
Symptom relief CompletedThis study tested whether a special anesthesia plan using dexmedetomidine and ketamine could reduce the need for opioid painkillers after laparoscopic hiatal hernia repair. Fifty adults having elective surgery were randomly assigned to receive either the opioid-sparing protocol o…
Phase: NA • Sponsor: Endeavor Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
-
Heart surgery recovery boost? drug may speed breathing tube removal
Symptom relief CompletedThis study tested whether a drug called sugammadex helps people wake up faster after heart surgery. 74 adults having heart surgery with a heart-lung machine received either sugammadex or a placebo. The main goal was to see if more patients could have their breathing tube removed …
Phase: PHASE3 • Sponsor: Endeavor Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
-
Simple muscle relaxant may spare women from catheters after pelvic surgery
Symptom relief CompletedThis study tested whether giving a muscle relaxant called tizanidine before pelvic surgery could help women urinate normally afterward. About 20 women having a specific type of pelvic repair took the drug, and researchers checked if they needed a catheter after surgery. The goal …
Phase: PHASE3 • Sponsor: Endeavor Health • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
-
Mindfulness may ease anxiety for breast cancer patients
Symptom relief CompletedThis study tested whether a brief mindfulness program could improve emotional well-being and quality of life in women with early-stage breast cancer. 42 women watched educational videos, listened to guided meditations, and wrote reflections before and after surgery. Researchers m…
Phase: NA • Sponsor: Endeavor Health • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
-
One pill before surgery may keep catheter away
Symptom relief CompletedThis study tested whether giving women a single dose of tamsulosin just before mid-urethral sling surgery could reduce the chance of needing a catheter after the procedure. About 179 women participated, and half received the drug while the other half got a placebo. The goal was t…
Phase: PHASE3 • Sponsor: Endeavor Health • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
-
Scientists unravel the mystery of menstrual cramps and pain relief
Knowledge-focused CompletedThis study looked at 183 women with menstrual pain to understand why it happens and how naproxen (a common painkiller) relieves it. Using MRI scans, researchers measured uterine activity, blood flow, and oxygen levels before and after taking naproxen or a placebo. The goal is to …
Phase: PHASE4 • Sponsor: Endeavor Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC