Colgate Palmolive
Clinical trials sponsored by Colgate Palmolive, explained in plain language.
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New toothbrush design fights mouth bacteria, study finds
Disease control CompletedThis study tested whether a manual toothbrush with a 360-degree cleaner design reduces bacteria in the whole mouth better than a standard flat-trim toothbrush. Fifty-six adults brushed with both types and had their saliva tested for bacteria before and after brushing. The goal wa…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Toothpaste and mouthwash combo takes on plaque in new study
Disease control CompletedThis study tested whether using a stannous fluoride toothpaste, a cetylpyridinium chloride mouthwash, and a battery-powered toothbrush together can reduce dental plaque and gingivitis (gum inflammation). 134 adults with at least 20 teeth and signs of gum disease used the regimen …
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New dual zinc toothpaste takes on plaque and gingivitis in 3-Month trial
Disease control CompletedThis study tested whether a new Colgate toothpaste with dual zinc can better control plaque and gingivitis (gum inflammation) compared to a standard cavity protection toothpaste. 86 adults with mild to moderate plaque and gum issues used one of the two toothpastes for three month…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New toothpaste and brush combo fights plaque and gum disease in 3-Month trial
Disease control CompletedThis study compared a stannous fluoride toothpaste paired with a newly designed toothbrush to a standard toothpaste and brush for reducing plaque and gingivitis (gum inflammation). 95 adults with mild to moderate gum issues used their assigned products for 3 months. Researchers m…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Gum guard: new PerioGard regimen takes on plaque and gingivitis
Disease control CompletedThis study tested whether a special dental care routine (PerioGard) works better than standard products for reducing plaque and gum inflammation. Eighty adults with mild to moderate gingivitis used either the PerioGard regimen or a regular fluoride toothpaste and mouthwash for th…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New toothpaste and mouthwash combo takes on plaque and gingivitis
Disease control CompletedThis study tested whether using a stannous fluoride toothpaste along with a cetylpyridinium chloride mouthwash and a manual toothbrush reduces dental plaque and gingivitis better than using regular fluoride toothpaste with a standard toothbrush. Eighty-two adults with mild gum di…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Toothbrush showdown: which brush beats plaque best?
Disease control CompletedThis completed Phase 2 study enrolled 84 adults with mild to moderate plaque and gingivitis. Participants were randomly assigned to use one of two manual toothbrush and toothpaste regimens at home for 6 weeks. Dentists measured plaque and gum inflammation at 1, 3, and 6 weeks to …
Phase: PHASE2 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Toothpaste showdown: which paste wins the cavity war?
Disease control CompletedThis study tested three different toothpastes to see how well they prevent cavities. Thirty-six healthy adults wore a special dental device for six weeks, and researchers measured changes in enamel hardness. The goal was to find which toothpaste best protects teeth from decay.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Toothpaste-Mouthwash combo beats regular brushing in gum health trial
Disease control CompletedThis study tested whether using a special toothpaste and mouthwash together with a manual toothbrush works better than regular fluoride toothpaste alone for reducing plaque and improving gum health. 90 adults with mild to moderate gum problems brushed twice daily for 12 weeks. Re…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Battery toothbrush beats manual in gum health showdown
Disease control CompletedThis completed Phase 3 study tested whether a battery toothbrush paired with a stannous fluoride toothpaste is more effective at reducing plaque and gingivitis than a regular fluoride toothpaste with a manual toothbrush. 130 adults with mild gum disease brushed twice daily for 12…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Tartar showdown: new toothpaste takes on regular fluoride
Disease control CompletedThis study tested whether a toothpaste with stannous fluoride is better at preventing tartar (hardened plaque) on teeth than a regular fluoride toothpaste. One hundred adults in Thailand brushed twice daily for 12 weeks. Researchers measured tartar buildup to see which toothpaste…
Phase: PHASE2, PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New mouthwash formula aims to fight plaque on dental implants
Disease control CompletedThis study tested a new mouthwash containing CPC, hyaluronic acid, and zinc lactate against a standard fluoride mouthwash. The goal was to see if it reduces plaque and prevents gum problems in adults with at least two dental implants. Eighty participants used the mouthwash for si…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Floss vs. mouthwash: which wins the battle against gum disease?
Disease control CompletedThis study tested how well floss and three different mouthwashes (one with essential oils and alcohol, one with essential oils but no alcohol, and one with CPC+Zn and no alcohol) reduce plaque and gum inflammation. 228 adults with mild to moderate gum disease took part. The goal …
Phase: PHASE4 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Smart toothbrush and app aim to stop Kids' cavities after surgery
Prevention CompletedThis study tested whether giving kids a connected toothbrush and a behavioral health app after cavity surgery helps them brush better and lowers dental costs. 93 children aged 4-7 who had surgery for cavities used the smart toothbrush and received motivational texts. Researchers …
Sponsor: Colgate Palmolive • Aim: Prevention
Last updated Jun 27, 2026 12:09 UTC
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New mouthwash takes on plaque and gum disease in 3-Month trial
Symptom relief CompletedThis study tested whether a new mouthwash can reduce dental plaque and help prevent gum problems better than a control mouthwash. 80 adults with mild to moderate gum inflammation and plaque used the product for three months. Researchers measured gum health and plaque levels at 2 …
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Gargle away the sniffles? study tests mouthwash against cold and flu
Symptom relief CompletedThis study tested whether gargling with a mouthwash containing cetylpyridinium chloride and zinc could reduce cold and flu symptoms. 150 healthy adults either brushed their teeth alone or brushed and then gargled with the mouthwash twice daily for 90 days. Participants tracked th…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Toothbrush showdown: which brush banishes stains best?
Symptom relief CompletedThis study tested how well different manual toothbrushes remove tooth stains. 80 healthy adults with some tooth staining brushed for 6 weeks. Researchers measured stain area and darkness to see which brush worked best.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Toothpaste showdown: can stannous fluoride beat sensitivity?
Symptom relief CompletedThis completed Phase 3 trial tested whether a toothpaste with stannous fluoride reduces tooth sensitivity better than a potassium-based toothpaste or regular fluoride toothpaste. 123 adults with sensitive teeth used one of the three toothpastes for 7 days. The study measured sens…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New toothpaste aims to soothe sensitive teeth
Symptom relief CompletedThis study tested whether a toothpaste with 5% potassium nitrate can reduce tooth sensitivity better than a regular fluoride toothpaste. 80 adults with sensitive teeth used one of the two toothpastes for eight weeks. The researchers measured sensitivity using a gentle touch and a…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New toothpaste aims to zap tooth pain fast
Symptom relief CompletedThis study tested whether a special toothpaste with 8% arginine (CSPR) can reduce tooth sensitivity better than a regular Colgate toothpaste. 95 adults with sensitive teeth used the toothpaste for 8 weeks. Researchers measured sensitivity using a gentle touch test and a cold air …
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New whitening system brightens smiles in clinical trial
Symptom relief CompletedThis study tested a new tooth whitening system used at the dentist's office. 180 healthy adults aged 18-70 took part. The goal was to see how well it whitens teeth compared to other whitening systems already on the market.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Whitening toothpaste with hydrogen peroxide tested for stain removal
Symptom relief CompletedThis study tested whether a toothpaste containing hydrogen peroxide removes tooth stains better than a regular fluoride toothpaste after just one brushing. 80 healthy adults brushed once under supervision, and their tooth stains were measured. The goal is to see if the hydrogen p…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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New toothpaste aims to soothe sensitive teeth in 8-week trial
Symptom relief CompletedThis study tested whether a toothpaste containing 8% arginine can reduce tooth sensitivity better than a regular cavity-protection toothpaste. Eighty adults with sensitive teeth used one of the two toothpastes for eight weeks. The main goal was to measure how much their sensitivi…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Gel could soothe pain after gum grafts, small study finds
Symptom relief CompletedThis study tested whether a gel made from hyaluronic acid (a natural substance in the body) can help heal wounds on the roof of the mouth after gum graft surgery. Thirty adults aged 18 to 70 took part, and researchers measured wound size and pain levels over six weeks. The goal w…
Phase: NA • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New toothpaste aims to soothe sensitive teeth
Symptom relief CompletedThis study tested whether a toothpaste containing 8% arginine can reduce tooth sensitivity better than a standard toothpaste. 84 adults with sensitive teeth brushed twice daily for 8 weeks. Researchers measured sensitivity using a gentle touch and a puff of air.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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New toothpaste promises 12-Hour fresh breath
Symptom relief CompletedThis study tested a toothpaste with stannous fluoride against a regular fluoride toothpaste to see which controls bad breath longer. 80 adults in Thailand brushed twice daily for 3 weeks, then had their breath scored by judges 12 hours after overnight brushing. The goal was to se…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Whitening showdown: 5% peroxide toothpaste takes on regular paste in One-Week trial
Symptom relief CompletedThis completed Phase 3 trial tested whether a Colgate toothpaste with 5% hydrogen peroxide and fluoride whitens teeth better than a toothpaste without hydrogen peroxide. Eighty adults brushed with one of the two toothpastes for one week. Researchers measured tooth color changes u…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 26, 2026 13:13 UTC
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Can a simple quiz boost your smile smarts?
Knowledge-focused CompletedThis study tested whether an online oral health quiz called Know Your OQ helps people learn more about taking care of their teeth and gums. 176 adults took the quiz and then answered questions about how easy it was to understand. The goal was to see if the quiz improves knowledge…
Sponsor: Colgate Palmolive • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC