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Toothbrush showdown: which brush banishes stains best?

NCT ID NCT06486974

Symptom relief Sponsor: Colgate Palmolive Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested how well different manual toothbrushes remove tooth stains. 80 healthy adults with some tooth staining brushed for 6 weeks. Researchers measured stain area and darkness to see which brush worked best.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

80 people

The number who actually took part.

Started

Sep 2024

Finished

Nov 2024

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Signed Informed Consent Form; * Male and female subjects, aged 18-70, inclusive; * Good general health and good oral health based on the opinion of the study investigator; * Presence of permanent natural anterior teeth (no veneers/crowns/restorations that may interfere with this study scoring procedures); * A minimum composite mean of 1.5 ≥ determined by the Lobene Tooth Stain Index; * Available for the duration of the study; * Clinical evidence of a tendency to form extrinsic stains on anterior teeth. Exclusion Criteria: * Presence of orthodontic appliances/retainers involving scorable teeth; * Presence of partial removable/fixed dentures and/or restorations involving scorable teeth; * Tumor(s) of the soft or hard tissues of the oral cavity; * Obvious signs of periodontal disease rampant caries, or any condition that the dental examiner considers exclusionary from the study; * Five or more carious lesions requiring immediate care; * Use of antibiotics, stain-inducing medications, and/or on any prescription that might interfere with the study outcome; * Concurrent participation in another clinical study; * Self-reported pregnancy and/or lactating women; * Have used professional whitening product within one (1) year or had a dental prophylaxis (professional dental cleaning) within thirty (30) days - prior to the start of the study; * History of allergies to oral care/personal care consumer products or their ingredients; * History of alcohol and/or drug abuse.

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Conditions

The condition(s) this trial relates to.

Tooth Discoloration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tooth discoloration

Contacts and locations

Locations

  • Spa Dental

    Santo Domingo, Dominican Republic

More trials for these conditions

Other studies related to the condition(s) this trial covers.