Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can root canals leave teeth discolored? study measures the change

NCT ID NCT07781969

Knowledge-focused Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 24, 2026 · Last updated Aug 28, 2026 · Updated 3 times

Summary

This study looks at whether root canal treatment causes noticeable tooth discoloration, and if the effect differs between teeth that were vital (live nerve) or devital (dead nerve) before treatment. Adults aged 18 to 65 with a maxillary premolar needing a root canal will receive standard treatment, and tooth color will be measured with a special device before and at 3, 6, and 9 months after. The goal is to track color changes over time and compare the two groups to better understand this common side effect.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Root canal treatment
What this could lead to
If successful, this could help dentists predict and prevent tooth discoloration after root canal therapy, improving cosmetic outcomes.
What could go wrong
This is a small observational study, so results may not apply to all teeth or patients. Color changes can vary widely, and the study does not test any treatment to prevent discoloration.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

52 people

The number who actually took part.

Started

Sep 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients presenting to the Department of Endodontics, Faculty of Dentistry, Marmara University, with maxillary first or second premolar teeth requiring root canal treatment constitute the study population. Eligible participants are evaluated clinically and radiographically according to predefined eligibility criteria. Before treatment, pulpal status is assessed using electric pulp testing and cold testing, and the included teeth are classified as vital or devital based on the findings.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals aged 18 to 65 years. * Systemically healthy individuals. * Patients with maxillary premolar teeth requiring root canal treatment. * Individuals who agree to participate in the study and provide written informed consent. Exclusion Criteria: * Teeth considered non-restorable. * Teeth with full-coverage crown restorations. * Teeth that have previously undergone root canal treatment. * Patients with a history of medication use that may cause tooth discoloration. * Teeth with restorations or caries involving more than two surfaces. * Teeth with restorations, caries, or loss of tooth structure involving the buccal surface. * Teeth with incomplete root development. * Teeth with developmental anomalies. * Teeth with a history of dental trauma. * Teeth with internal or external root resorption. * Teeth with advanced periodontal destruction. * Individuals consuming more than two cups per day of coffee, tea, wine, or fruit juices that may cause tooth discoloration. * Teeth with amalgam restorations. * Current smokers. * Pregnant or breastfeeding women. * Individuals younger than 18 years or older than 65 years.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Tooth discoloration are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Tooth Discoloration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tooth discoloration Tooth discoloration following root canal treatment

Contacts and locations

Locations

  • Marmara University Faculty of Dentistry

    Istanbul, Istanbul, 34854, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.