Whitening showdown: 5% peroxide toothpaste takes on regular paste in One-Week trial
NCT ID NCT06957249
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed Phase 3 trial tested whether a Colgate toothpaste with 5% hydrogen peroxide and fluoride whitens teeth better than a toothpaste without hydrogen peroxide. Eighty adults brushed with one of the two toothpastes for one week. Researchers measured tooth color changes using a standard shade guide. The goal was to see if the peroxide toothpaste provides a noticeable whitening boost.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
5% hydrogen peroxide toothpaste
What this could lead to
If it works, this could confirm that a 5% hydrogen peroxide toothpaste whitens teeth more effectively than a non-whitening toothpaste.
What could go wrong
This is a short, small trial (80 people, one week) focused only on tooth shade, not long-term safety or durability. Results may not apply to everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Consumer Research Consulting, LLC
Melbourne, Florida, 32940, United States