Whitening showdown: 5% peroxide toothpaste takes on regular paste in One-Week trial
NCT ID NCT06957249
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed Phase 3 trial tested whether a Colgate toothpaste with 5% hydrogen peroxide and fluoride whitens teeth better than a toothpaste without hydrogen peroxide. Eighty adults brushed with one of the two toothpastes for one week. Researchers measured tooth color changes using a standard shade guide. The goal was to see if the peroxide toothpaste provides a noticeable whitening boost.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 5% hydrogen peroxide toothpaste
- What this could lead to
- If it works, this could confirm that a 5% hydrogen peroxide toothpaste whitens teeth more effectively than a non-whitening toothpaste.
- What could go wrong
- This is a short, small trial (80 people, one week) focused only on tooth shade, not long-term safety or durability. Results may not apply to everyone.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Consumer Research Consulting, LLC
Melbourne, Florida, 32940, United States
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