Children's Hospital Of Fudan University

This study tested whether the cholesterol-lowering drug atorvastatin is safe and effective for treating skin growths called xanthomas in children with Alagille Syndrome. It involved 15 children and teenagers, who took the drug for up to 6 months while doctors monitored changes in…

This study tested whether hydroxychloroquine (HCQ), a medication with anti-inflammatory properties, could help children with a rare, serious lung disease caused by specific genetic mutations. The trial involved 25 children with this condition to see if HCQ could improve their bre…

This study tested whether a moisturizer containing postbiotics (substances from 'friendly' bacteria and yeast) could help prevent eczema from coming back in children aged 0-6 years. It compared this special lotion to stopping moisturizer use entirely after getting the eczema unde…

This small, early-stage study tested whether a specially designed probiotic (CBT102-A) could safely lower harmful phenylalanine levels in the blood of children with PKU. Fifteen children aged 3-17 took either the probiotic or a placebo for 20 days. The main goal was to see if the…

This study looked at whether having a congenital heart defect affects long-term health and quality of life for children who have survived blood cancers like leukemia. Researchers followed 800 survivors to compare those with heart defects to those without, tracking health outcomes…

This study aimed to understand the situation of children in China who need mechanical ventilation (breathing machine support) for a long time—21 days or more. Researchers looked at 346 children across multiple hospitals to find out the main medical causes, how long children neede…

This study aimed to understand if key nutrients in a mother's body during pregnancy, like folate and vitamin D, are connected to whether her baby develops atopic dermatitis (eczema) in the first 6 months of life. Researchers followed 487 pregnant women in Shanghai, checking their…