Children's Hospital Of Fudan University

This study tests whether adding a traditional Chinese medicine herbal formula (Sanghe Jianghuo Granules) to standard Western treatment can better manage precocious puberty in girls aged 5 to 9. The goal is to slow down early breast development and bone aging, and improve final he…

This study aimed to see if operating on a congenital spine deformity (hemivertebra) in children aged 3-5 is better than waiting until after age 5. Children would have been randomly assigned to early surgery or bracing followed by later surgery. However, the study was withdrawn be…

This study tests whether cyclophosphamide, a drug that calms the immune system, can reduce insulin needs in people with a rare condition that causes fat loss (lipodystrophy) and type 1 diabetes. Ten participants will receive the treatment, and researchers will measure how much in…

This study tests a new way to manage blood flow and oxygen in children right after heart surgery. The goal is to help their bodies use oxygen better during the critical first 8 hours, which may prevent dangerous drops in blood pressure or heart function. About 300 children weighi…

This study planned to test whether a milk powder rich in medium-chain fatty acids could improve nutrition and health in infants with cholestatic liver disease. Researchers aimed to compare the special formula to regular milk powder in 64 infants under 6 months old. However, the s…

This study tests whether special 'peripheral focus-out' glasses can prevent nearsightedness (myopia) in Chinese children aged 6 to 8. Over two years, 160 children will wear the glasses at least 8 hours a day. Researchers will measure changes in their vision to see if the glasses …

This study follows 1,000 children from birth to age 3 to see how their gut microbiome develops and how it relates to growth and health. Researchers will collect stool samples and measurements at regular intervals, along with details about diet, environment, and medical history. T…

This study compares social cognitive abilities—like recognizing emotions and understanding others' thoughts—in children with autism versus typically developing children aged 2.5 to 14 years. Researchers will use behavioral tasks and eye-tracking to map developmental patterns. The…

This study watches 428 children aged 1 day to 18 years who get a mini-midline catheter, a type of IV. Researchers track how often it works on the first try, how long it stays in, and any problems like infection or clotting. The goal is to learn which kids benefit most and how to …

This study follows 456 mothers and their children for 5 years to see if certain chemicals in the mother's blood during pregnancy are linked to the child developing eczema. Researchers will check children's skin regularly and track any eczema diagnosis. The goal is to understand p…

This study looks at whether a decision tree can help Child Life Specialists do their jobs better. Specialists in the intervention group use the decision tree to guide their care, while others rely on their own experience. The goal is to see if the tool improves specialists' knowl…

This study aims to find early biological markers that can predict muscle weakness in children who need a breathing machine in the intensive care unit. About 500 children will be observed to see who develops this condition. The goal is to create a warning system so doctors can int…

This study is developing an early warning model to predict ICU-acquired weakness in children who need mechanical ventilation. Researchers will track 1,500 children in the PICU, looking for biomarkers and other signs that could forecast muscle weakness. The goal is to move from di…