New study aims to predict muscle weakness in kids on ventilators before it strikes

NCT ID NCT07150637

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Children's Hospital of Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is developing an early warning model to predict ICU-acquired weakness in children who need mechanical ventilation. Researchers will track 1,500 children in the PICU, looking for biomarkers and other signs that could forecast muscle weakness. The goal is to move from diagnosing weakness after it happens to predicting it early, which could improve recovery and reduce long-term disability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a tool that predicts muscle weakness in critically ill children before symptoms appear, allowing earlier treatment and reducing long-term disability.
What could go wrong: This is an observational study, not a treatment trial. The model may not be accurate enough for real-world use, and results may not apply to all children or hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

critical illness polyneuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ICU ACQUIRED WEAKNESS

Contacts and locations

Locations

Children' hospital of Fudan university

Shanghai, Shanghai Municipality, 201102, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.