Heart defects may complicate recovery for childhood cancer survivors

NCT ID NCT07249138

Completed Knowledge-focused Sponsor: Children's Hospital of Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 800 children who survived blood cancer to see if having a congenital heart defect raises their risk of death or other health problems later in life. Researchers also checked for shared genetic links between the two conditions. The goal is to better understand and care for these survivors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better predict and manage long-term health problems in childhood cancer survivors who also have heart defects.
What could go wrong: This is an observational study, so it cannot prove cause and effect. Results may not apply to all survivors, and the findings might not lead to direct changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congenital heart disease hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONGENITAL HEART DISEASE (CHD) HEMATOLOGIC MALIGNANCY

Contacts and locations

Locations

Beijing Children's Hospital

Beijing, China
Children's Hospital of Fudan University

Shanghai, China
Children's Hospital of Soochow University

Suzhou, China
Guangzhou Women and Children's Medical Center

Guangzhou, China
Inner Mongolia Maternal and Child Health Care Hospital

Hohhot, China
Nanjing Children's Hospital

Nanjing, China
Northwest Women's and Children's Hospital

Xi'an, China
Shandong Provincial Hospital

Jinan, China
Shanghai Children's HospitalShanghai Children's Hospital

Shanghai, China
Shanxi Children's Hospital

Taiyuan, China
The Affiliated Hospital of Qingdao University

Qingdao, China
The First Affiliated Hospital of Guangxi Medical University

Nanning, China
The First Affiliated Hospital of Zhengzhou University

Zhengzhou, China
The Fourth Hospital of Hebei Medical University

Shijiazhuang, China
The Third Xiangya Hospital of Central South University

Changsha, China
Tongji Hospital of Huazhong University of Science and Technology

Wuhan, China
Union Hospital of Huazhong University of Science and Technology

Wuhan, China
Wuhan Children's Hospital

Wuhan, China

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