Gene-Editing breakthrough offers hope for blood disorder patients

NCT ID NCT06065189

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a new gene-edited stem cell transplant in 2 children with severe β-thalassemia, a serious blood disorder requiring lifelong transfusions. The treatment aims to help the body produce healthy red blood cells and reduce or stop the need for transfusions. Researchers monitored safety, engraftment, and blood counts to see if the approach is feasible.

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Conditions

The condition(s) this trial relates to.

beta thalassemia beta-thalassemia major

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital of Fudan University

    Shanghai, Shanghai Municipality, 201102, China