Could a ketamine drug ease rett syndrome?
NCT ID NCT06199700
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested esketamine, a form of ketamine, in 3 girls with Rett syndrome. The goal was to see if weekly infusions over five weeks could improve symptoms and be safe. The trial is complete, but with only 3 participants, it's too small to draw firm conclusions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Esketamine (a form of ketamine)
- What this could lead to
- If it works, this could point toward a treatment that eases some symptoms of Rett syndrome.
- What could go wrong
- This is a very early trial with only 3 participants, so results may not apply to others. Esketamine can cause side effects like high blood pressure or sedation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Xiamen Children's Hospital (Children's Hospital of Fudan University at Xiamen)
Xiamen, Fujian, 361006, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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