Could a ketamine drug ease rett syndrome?
NCT ID NCT06199700
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested esketamine, a form of ketamine, in 3 girls with Rett syndrome. The goal was to see if weekly infusions over five weeks could improve symptoms and be safe. The trial is complete, but with only 3 participants, it's too small to draw firm conclusions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Esketamine (a form of ketamine)
What this could lead to
If it works, this could point toward a treatment that eases some symptoms of Rett syndrome.
What could go wrong
This is a very early trial with only 3 participants, so results may not apply to others. Esketamine can cause side effects like high blood pressure or sedation.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Xiamen Children's Hospital (Children's Hospital of Fudan University at Xiamen)
Xiamen, Fujian, 361006, China