Heart-Saving combo: steroid plus standard therapy may shield kids from kawasaki damage

NCT ID NCT04078568

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether adding a steroid called prednisolone to the usual treatment (immunoglobulin and aspirin) could reduce heart artery damage in children with Kawasaki disease. Over 3,200 children took part. The goal was to see if the combination therapy lowers the chance of coronary artery lesions, which can lead to long-term heart problems.

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Conditions

The condition(s) this trial relates to.

Kawasaki disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Anhui Children's Hospital

    Hefei, Anhui, 230022, China

  • Bengbu First People's Hopital

    Bengbu, Anhui, 233000, China

  • Chengdu Women's and Children's Central Hospital

    Chengdu, Sichuan, 610074, China

  • Children's Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400014, China

  • Children's Hospital of Fudan University

    Shanghai, Shanghai Municipality, 201102, China

  • Children's Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210008, China

  • Children's Hospital, Capital Institute of Pediatrics

    Beijing, Beijing Municipality, 100020, China

  • Children's hospital of Soochow University

    Suzhou, Jiangsu, 215003, China

  • Guangzhou Women and Children's Medical Center

    Guangzhou, Guangdong, 510623, China

  • Hangzhou First people's Hospital

    Hangzhou, Zhejiang, 310006, China

  • Henan Children's Hospital

    Zhengzhou, Henan, 450018, China

  • Hunan Provincial People's Hospital

    Changsha, Hunan, 410002, China

  • Inner Mongolia People's Hospital

    Hohhot, Inner Mongolia, 010017, China

  • Jiangxi Provincial Children's Hospital

    Nanchang, Jiangxi, 330006, China

  • Kaifeng Children's Hospital

    Kaifeng, Henan, 475000, China

  • Lanzhou University Second Hospital

    Lanzhou, Gansu, 730030, China

  • Liuzhou Maternity and Children Healthcare Hospital

    Liuzhou, Guangxi, 545001, China

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250012, China

  • Qingdao Women and Children's Hospital

    Qingdao, Shandong, 266011, China

  • Qingdao Women and Children's Hospital (Liaoyang West Road)

    Qingdao, Shandong, 266011, China

  • Shanghai Children's Hospital

    Shanghai, Shanghai Municipality, 200040, China

  • Shengjing Hospital of China Medical University

    Shenyang, Liaoning, 110004, China

  • Shenzhen Children's Hospital

    Shenzhen, Guangdong, 518038, China

  • Sichuan Provincial People's Hospital

    Chengdu, Sichuan, 610072, China

  • Sun Yat-sen Memorial Hospital

    Guangzhou, Guangdong, 510120, China

  • Taihe Hospital Affiliated Hospital of Hubei University of Medicine

    Shiyan, Hubei, 442000, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The Third Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

  • Union Hospital,Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • Xi'an Children's Hospital

    Xi'an, Shaanxi, 710003, China

  • Xiamen Children's Hospital

    Xiamen, Fujian, 361006, China

  • Xuzhou Children's Hospital

    Xuzhou, Jiangsu, 221006, China

  • Yuying Children's Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325027, China

  • the First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China