Heart-Saving combo: steroid plus standard therapy may shield kids from kawasaki damage

NCT ID NCT04078568

Completed Disease control Sponsor: Children's Hospital of Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding a steroid called prednisolone to the usual treatment (immunoglobulin and aspirin) could reduce heart artery damage in children with Kawasaki disease. Over 3,200 children took part. The goal was to see if the combination therapy lowers the chance of coronary artery lesions, which can lead to long-term heart problems.

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Conditions

The condition(s) this trial relates to.

Kawasaki disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KAWASAKI DISEASE

Contacts and locations

Locations

Anhui Children's Hospital

Hefei, Anhui, 230022, China
Bengbu First People's Hopital

Bengbu, Anhui, 233000, China
Chengdu Women's and Children's Central Hospital

Chengdu, Sichuan, 610074, China
Children's Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400014, China
Children's Hospital of Fudan University

Shanghai, Shanghai Municipality, 201102, China
Children's Hospital of Nanjing Medical University

Nanjing, Jiangsu, 210008, China
Children's Hospital, Capital Institute of Pediatrics

Beijing, Beijing Municipality, 100020, China
Children's hospital of Soochow University

Suzhou, Jiangsu, 215003, China
Guangzhou Women and Children's Medical Center

Guangzhou, Guangdong, 510623, China
Hangzhou First people's Hospital

Hangzhou, Zhejiang, 310006, China
Henan Children's Hospital

Zhengzhou, Henan, 450018, China
Hunan Provincial People's Hospital

Changsha, Hunan, 410002, China
Inner Mongolia People's Hospital

Hohhot, Inner Mongolia, 010017, China
Jiangxi Provincial Children's Hospital

Nanchang, Jiangxi, 330006, China
Kaifeng Children's Hospital

Kaifeng, Henan, 475000, China
Lanzhou University Second Hospital

Lanzhou, Gansu, 730030, China
Liuzhou Maternity and Children Healthcare Hospital

Liuzhou, Guangxi, 545001, China
Qilu Hospital of Shandong University

Jinan, Shandong, 250012, China
Qingdao Women and Children's Hospital

Qingdao, Shandong, 266011, China
Qingdao Women and Children's Hospital (Liaoyang West Road)

Qingdao, Shandong, 266011, China
Shanghai Children's Hospital

Shanghai, Shanghai Municipality, 200040, China
Shengjing Hospital of China Medical University

Shenyang, Liaoning, 110004, China
Shenzhen Children's Hospital

Shenzhen, Guangdong, 518038, China
Sichuan Provincial People's Hospital

Chengdu, Sichuan, 610072, China
Sun Yat-sen Memorial Hospital

Guangzhou, Guangdong, 510120, China
Taihe Hospital Affiliated Hospital of Hubei University of Medicine

Shiyan, Hubei, 442000, China
The First Hospital of Jilin University

Changchun, Jilin, 130021, China
The Third Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, 450052, China
Union Hospital,Tongji Medical College of Huazhong University of Science and Technology

Wuhan, Hubei, 430022, China
Xi'an Children's Hospital

Xi'an, Shaanxi, 710003, China
Xiamen Children's Hospital

Xiamen, Fujian, 361006, China
Xuzhou Children's Hospital

Xuzhou, Jiangsu, 221006, China
Yuying Children's Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, 325027, China
the First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, 450052, China

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