Steroid combo may shield kids' hearts from kawasaki damage

NCT ID NCT04078568

First seen Nov 19, 2025 · Last updated May 14, 2026 · Updated 23 times

Summary

This study looked at whether adding a steroid called prednisolone to the usual treatment (immunoglobulin and aspirin) could reduce damage to the heart's arteries in children with Kawasaki disease. Over 3,200 children were enrolled. The main goal was to see if fewer children developed coronary artery problems one month after treatment.

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Contacts and locations

Locations

  • Anhui Children's Hospital

    Hefei, Anhui, 230022, China

  • Bengbu First People's Hopital

    Bengbu, Anhui, 233000, China

  • Chengdu Women's and Children's Central Hospital

    Chengdu, Sichuan, 610074, China

  • Children's Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400014, China

  • Children's Hospital of Fudan University

    Shanghai, Shanghai Municipality, 201102, China

  • Children's Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210008, China

  • Children's Hospital, Capital Institute of Pediatrics

    Beijing, Beijing Municipality, 100020, China

  • Children's hospital of Soochow University

    Suzhou, Jiangsu, 215003, China

  • Guangzhou Women and Children's Medical Center

    Guangzhou, Guangdong, 510623, China

  • Hangzhou First people's Hospital

    Hangzhou, Zhejiang, 310006, China

  • Henan Children's Hospital

    Zhengzhou, Henan, 450018, China

  • Hunan Provincial People's Hospital

    Changsha, Hunan, 410002, China

  • Inner Mongolia People's Hospital

    Hohhot, Inner Mongolia, 010017, China

  • Jiangxi Provincial Children's Hospital

    Nanchang, Jiangxi, 330006, China

  • Kaifeng Children's Hospital

    Kaifeng, Henan, 475000, China

  • Lanzhou University Second Hospital

    Lanzhou, Gansu, 730030, China

  • Liuzhou Maternity and Children Healthcare Hospital

    Liuzhou, Guangxi, 545001, China

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250012, China

  • Qingdao Women and Children's Hospital

    Qingdao, Shandong, 266011, China

  • Qingdao Women and Children's Hospital (Liaoyang West Road)

    Qingdao, Shandong, 266011, China

  • Shanghai Children's Hospital

    Shanghai, Shanghai Municipality, 200040, China

  • Shengjing Hospital of China Medical University

    Shenyang, Liaoning, 110004, China

  • Shenzhen Children's Hospital

    Shenzhen, Guangdong, 518038, China

  • Sichuan Provincial People's Hospital

    Chengdu, Sichuan, 610072, China

  • Sun Yat-sen Memorial Hospital

    Guangzhou, Guangdong, 510120, China

  • Taihe Hospital Affiliated Hospital of Hubei University of Medicine

    Shiyan, Hubei, 442000, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The Third Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

  • Union Hospital,Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • Xi'an Children's Hospital

    Xi'an, Shaanxi, 710003, China

  • Xiamen Children's Hospital

    Xiamen, Fujian, 361006, China

  • Xuzhou Children's Hospital

    Xuzhou, Jiangsu, 221006, China

  • Yuying Children's Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325027, China

  • the First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

Conditions

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