New drug combo aims to shield Children's hearts from kawasaki disease
NCT ID NCT07686770
First seen Jul 07, 2026 · Last updated Jul 21, 2026 · Updated 3 times
Summary
This study tests whether adding a drug called firsekibart to the standard treatment (IVIG and aspirin) can better prevent coronary artery damage in children with Kawasaki disease. Kawasaki disease causes inflammation in blood vessels, especially those supplying the heart, and can lead to serious heart problems. The trial will enroll 90 children diagnosed within 10 days of fever onset and compare outcomes like coronary artery lesions and fever duration between the two treatment groups.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- firsekibart (an IL-1β receptor antagonist) plus intravenous immunoglobulin (IVIG) and aspirin
- What this could lead to
- If successful, this combination could reduce the risk of lasting heart damage in children with Kawasaki disease.
- What could go wrong
- This is an early exploratory trial with only 90 children, so results may not be conclusive. Adding a new drug also carries unknown side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital of Fudan University
Shanghai, Shanghai Municipality, 201102, China
Contact
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Jiangxi Provincial Children's Hospital
Nanchang, Jiangxi, 330006, China
Contact
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