Centre Hospitalier De L'université De Montréal (chum)

This phase II trial is testing whether argon plasma coagulation (APC) can safely and effectively treat high-grade anal lesions (AIN 2/3) in HIV-positive men who have sex with men. APC uses ionized argon gas to deliver a controlled electrical current that destroys abnormal cells. …

This trial is testing whether adding targeted radiation (SBRT) to two immunotherapy drugs, durvalumab and tremelimumab, can better control metastatic head and neck cancer. The study includes adults with this cancer that has spread, and the radiation is given between cycles of the…

This early-stage study tested whether infliximab, a drug usually given through a vein, can be safely used as eye drops for sterile corneal melt. This condition causes the clear front part of the eye to thin, which can lead to blindness. Seven adults with this condition received t…

This study tested whether giving liver transplant patients a daily high-protein drink for 12 weeks helps them maintain muscle mass. Thirty patients on the transplant list took part. Researchers measured muscle mass with CT scans and tracked how well patients stuck with the drink.…

This trial tests whether using a technique called hybrid argon plasma coagulation (h-APC) on the edges of the removal site can prevent colon polyps from growing back after endoscopic mucosal resection (EMR). EMR is a standard procedure for removing large polyps, but when polyps a…

This study tested a non-silicone gel sheet on burn scars in 49 adult survivors. The goal was to see if it reduces redness, thickness, pain, and itch compared to no treatment. Participants used the gel on one scar area while another similar scar was left untreated. The study is co…

This trial tests whether an ultrasound-guided injection of alcohol and a numbing agent around the celiac ganglia can relieve pain in people newly diagnosed with inoperable pancreatic cancer. Participants receive either the nerve block or a sham procedure, alongside standard pain …

This study looked at whether serial casting (applying a cast that is changed weekly) can improve arm and hand movement in adults who have stiff joints from burn scars. Twelve burn survivors with limited range of motion received one week of usual care, then serial casting if neede…

This study tested two different methods (paracoracoid vs. costoclavicular) for placing tiny catheters near nerves to deliver pain medicine after hand surgery. 140 adults having outpatient hand surgery took part. The goal was to see which approach provides better numbness and pain…

This pilot study tested a mobile app called iCanChange in 100 young adults (ages 18-35) with psychosis and cannabis use disorder. The app uses motivational interviewing and cognitive behavioral therapy techniques through short interactive modules. The main goal was to see if the …

This study tested whether an online service that provides personalized low-FODMAP menus and nutritional support can improve quality of life and symptoms in people with irritable bowel syndrome (IBS). Forty participants followed the diet for six months using a web platform. Resear…

This study tests if a less invasive ultrasound-guided needle procedure can work as well as mini-open surgery for chronic tennis elbow that hasn't improved with rest or therapy. Sixty-four workers with persistent elbow pain will be randomly assigned to one of the two treatments. T…

This study investigates whether using a lower, more natural eye pressure during cataract surgery reduces trauma to the cornea compared to traditional high-pressure methods. The Active Sentry device helps maintain stable pressure by sensing changes in the eye. Researchers will mea…

This study will measure how many women at a high-risk pregnancy clinic experience postpartum depression. Researchers will use a standard questionnaire called the Edinburgh Postnatal Depression Scale (EPDS) to screen 100 women who gave birth 4 weeks to 6 months ago. The goal is to…

This study aims to establish normal lung stretch values using ultrasound in 81 healthy volunteers. Researchers will measure how the lungs expand at different air volumes to create a baseline. This could eventually help doctors adjust ventilators to avoid lung injury in patients.

This pilot study tested whether using ultrasound to check fluid tolerance is feasible in hospitalized patients with acute kidney injury (AKI). 80 non-ICU adults were randomly assigned to receive either standard care or an ultrasound-guided fluid assessment. The main goal was to s…