Centre Henri Becquerel
Clinical trials sponsored by Centre Henri Becquerel, explained in plain language.
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Tailored radiation boosts lung cancer control in new trial
Disease control CompletedThis study tested whether giving personalized radiation doses based on PET scans during treatment could improve local control in patients with inoperable stage III non-small cell lung cancer. 158 participants received either standard radiation or a higher, tailored dose to areas …
Phase: PHASE2 • Sponsor: Centre Henri Becquerel • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Can a daily antibiotic stop deadly infections in blood cancer patients?
Disease control CompletedThis study tested whether the antibiotic levofloxacin can prevent fevers and infections in people with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) who are receiving the chemotherapy drug azacitidine. Infections are a major risk for these patients. The trial ran…
Phase: PHASE3 • Sponsor: Centre Henri Becquerel • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Touch therapy calms nerves before breast biopsy, small study suggests
Symptom relief CompletedThis study tested a manual acupressure technique called Energy Resonance by Cutaneous Stimulation (RESC) to see if it could lower anxiety in 57 women about to undergo a breast macrobiopsy. Participants received a RESC session before the procedure, and their anxiety was measured u…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Timing of extra care may boost quality of life in myeloma patients
Symptom relief CompletedThis study looked at whether starting supportive care (like meetings with a nurse, psychologist, or dietitian) right after a multiple myeloma diagnosis helps patients feel better compared to waiting 6 months. Twenty patients took part, and researchers measured their quality of li…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can a fentanyl spray stop pain during cancer radiation?
Symptom relief CompletedThis completed Phase 3 trial tested whether a fentanyl spray (Pecfent) could prevent pain when moving patients with bone metastases during radiotherapy. 39 adults with cancer that spread to bone and who had pain during positioning for radiation took part. The study compared fenta…
Phase: PHASE3 • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Exercise boosts brain power in breast cancer survivors?
Symptom relief CompletedThis study looked at whether a structured exercise program (adapted physical activity) could improve thinking and quality of life in women treated for locally advanced breast cancer. 37 women who had chemotherapy and reported memory or concentration problems took part. Half start…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can a simple blood test predict chemo side effects in brain cancer patients?
Knowledge-focused CompletedThis completed Phase 2 study looked at 244 glioblastoma patients to see if platelet counts during radiation and chemotherapy could predict who would develop dangerously low platelets later. The goal was to create a monitoring plan for high-risk patients. No new drug or treatment …
Phase: PHASE2 • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Blood mutation may reveal hidden lymphoma after treatment
Knowledge-focused CompletedThis study looked at 137 adults with newly diagnosed classical Hodgkin lymphoma to see if a specific genetic change (XPO1 E571K) found in their blood could signal whether cancer remains after chemotherapy. Researchers compared the blood test results with standard PET scans to mea…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Blood test could replace bone marrow biopsy for rare blood cancer monitoring
Knowledge-focused CompletedThis study looked at 45 adults newly diagnosed with Waldenström's disease, a rare blood cancer. Researchers compared different lab methods to detect a common genetic mutation (MYD88 L265P) in blood and bone marrow samples. The goal was to find less invasive ways to diagnose and t…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Timing tumor DNA tests after chemo: a small study
Knowledge-focused CompletedThis study measured how levels of circulating tumor DNA (ctDNA) change in the hours after the first round of chemotherapy in 24 people with diffuse large B cell lymphoma. The goal was to find the best time to take blood samples for monitoring the cancer. Researchers hope that a b…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Can a simple scan predict lung cancer treatment success?
Knowledge-focused CompletedThis study looked at 40 people with advanced non-small cell lung cancer who were starting treatment with the drug pembrolizumab. Researchers used special PET scans after each of the first three doses to see how the cancer's metabolism changed. The goal was to find out if early sc…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New imaging combo could reveal hidden tumor oxygen levels
Knowledge-focused CompletedThis study looked at 16 people with a type of throat cancer (squamous cell carcinoma of the oropharynx). Researchers used two types of scans—PET and MRI—to measure oxygen levels inside the tumors. They also checked tumor samples under a microscope to see if the scan results match…
Phase: PHASE2 • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Swallow a thermometer? new study tests pill that takes your temperature from inside
Knowledge-focused CompletedThis study tested whether a small, swallowable capsule can accurately measure body temperature in 30 hospitalized patients with blood cancers who have very low immunity (neutropenia). Researchers compared the capsule's temperature readings to standard ear thermometer measurements…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New imaging combo could sharpen prostate cancer radiation
Knowledge-focused CompletedThis study tested whether combining PET-CT and MRI scans (called trimodality imaging) can better define the target area for radiotherapy in high-risk prostate cancer. Twenty patients received both standard scans and the new combined scan before treatment. Researchers compared the…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New imaging technique may spot lung cancer recurrence sooner
Knowledge-focused CompletedThis study looked at whether a special type of PET scan called parametric imaging can better predict if lung cancer will come back within a year after chemoradiation. Researchers compared it to standard PET scans in 40 patients with non-small cell lung cancer. The goal is to see …
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Custom DNA blood test could spot head and neck cancer return
Knowledge-focused CompletedThis study tested a personalized blood test that looks for tumor DNA in 40 patients with advanced head and neck cancer. The goal was to see if the test could help predict how the disease will progress and detect if the cancer comes back after treatment. Researchers took blood sam…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New imaging tracer could reveal how chemotherapy affects lymphoma blood vessels
Knowledge-focused CompletedThis study tested a special PET scan tracer called 18F-RGD-K5 in 21 people with lymphoma. The tracer highlights blood vessel growth (angiogenesis) in tumors. Scans were done before and after two rounds of chemotherapy to see how the tumors changed. The goal was to learn whether t…
Phase: PHASE2 • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC