Centre Henri Becquerel
Clinical trials sponsored by Centre Henri Becquerel, explained in plain language.
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Antibiotic shield tested for blood cancer patients on azacitidine
Disease control CompletedThis study looked at whether giving the antibiotic levofloxacin can prevent serious infections in people with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) who are being treated with azacitidine. Infections are a major risk for these patients. The study enrolled…
Phase: PHASE3 • Sponsor: Centre Henri Becquerel • Aim: Disease control
Last updated May 18, 2026 12:06 UTC
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Tailored radiation boosts lung cancer control in Mid-Treatment trial
Disease control CompletedThis study tested a personalized approach to radiation therapy for people with stage III lung cancer that cannot be removed by surgery. During standard chemo-radiation, doctors used PET scans to see how the tumor was responding and adjusted the radiation dose to target stubborn a…
Phase: PHASE2 • Sponsor: Centre Henri Becquerel • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New pain prevention strategy for bone metastasis patients during radiotherapy
Symptom relief CompletedThis study tested whether a fentanyl lozenge (a strong, fast-acting painkiller) can prevent pain when patients with bone metastasis are moved into position for radiation therapy. 39 adults with bone cancer spread and significant pain during positioning took part. The goal was to …
Phase: PHASE3 • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated May 25, 2026 09:53 UTC
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Exercise boosts brain power in breast cancer survivors, study finds
Symptom relief CompletedThis study looked at whether a personalized exercise program could help improve memory, focus, and overall well-being in women treated for locally advanced breast cancer. 37 women who had chemotherapy and surgery took part. The goal was to see if exercise could reduce the mental …
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated May 25, 2026 09:52 UTC
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Gentle acupressure calms nerves before breast biopsy, study finds
Symptom relief CompletedThis study tested a simple, non-invasive acupressure technique called Energy Resonance by Cutaneous Stimulation (RESC) to help reduce anxiety in women before a breast biopsy. 57 women having their first breast biopsy for suspected cancer took part. The goal was to see if this gen…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated May 25, 2026 09:44 UTC
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Timing of extra care may boost myeloma quality of life
Symptom relief CompletedThis study looked at whether starting paramedical supportive care (like counseling or nutrition advice) right at diagnosis helps multiple myeloma patients more than waiting six months. Twenty patients took part, and researchers measured their quality of life using a special quest…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated May 22, 2026 13:55 UTC
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Tumor DNA spike after chemo may reveal hidden mutations
Knowledge-focused CompletedThis study looked at how levels of tumor DNA in the blood change in the hours after the first dose of chemotherapy for diffuse large B-cell lymphoma. Researchers wanted to find the best time to take blood samples for monitoring. The study included 24 adults who were starting trea…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 25, 2026 09:58 UTC
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New imaging technique may spot lung cancer recurrence sooner
Knowledge-focused CompletedThis study looked at 40 adults with non-small cell lung cancer who had chemoradiation. Researchers compared a special type of PET scan (parametric imaging) to standard PET scans to see which better predicts if the cancer will come back within a year. The goal was to find a more a…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 25, 2026 09:58 UTC
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Custom blood test could spot head and neck cancer relapse early
Knowledge-focused CompletedThis study looked at whether a personalized blood test can find tiny bits of tumor DNA (ctDNA) in patients with advanced head and neck cancer. Forty patients provided blood samples before surgery, after surgery, and during 18 months of follow-up. The goal was to see if tracking c…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 25, 2026 09:57 UTC
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New imaging combo could reveal hidden tumor oxygen levels
Knowledge-focused CompletedThis study looked at 16 people with a type of throat cancer (oropharynx squamous cell carcinoma). Researchers compared two imaging methods—PET scans and MRI—to measure oxygen levels (hypoxia) in tumors. They also checked tissue samples to see if the scans matched what was seen un…
Phase: PHASE2 • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 25, 2026 09:57 UTC
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Blood test may replace painful bone marrow biopsy for rare cancer monitoring
Knowledge-focused CompletedThis study looked at 45 people newly diagnosed with Waldenström's disease, a rare blood cancer. Researchers compared different methods to detect a common genetic mutation (MYD88 L265P) in blood and bone marrow samples. The goal was to see if a simple blood test could replace inva…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 25, 2026 09:52 UTC
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Blood test may predict chemo side effects in brain cancer patients
Knowledge-focused CompletedThis study looked at 244 people with glioblastoma, a serious brain cancer, to see if changes in platelet counts during early treatment could predict later blood problems. The goal was to create a monitoring plan to catch low platelet levels early. The study did not test a new tre…
Phase: PHASE2 • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 25, 2026 09:52 UTC
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Triple scan may sharpen radiation targeting for prostate cancer
Knowledge-focused CompletedThis study tested whether combining three types of scans (PET-CT, choline, and MRI) can better map prostate cancer for radiation therapy. Twenty high-risk prostate cancer patients received the triple scan, and researchers compared the tumor outlines to those from standard scans. …
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 25, 2026 09:51 UTC
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Can a PET scan predict lung cancer treatment success after just one dose?
Knowledge-focused CompletedThis study looked at 40 people with advanced non-small cell lung cancer whose tumors have high PD-L1 levels. They received the immunotherapy drug pembrolizumab, and researchers used PET scans after the first dose to see if early changes in tumor activity could predict whether the…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Pill thermometer tested in blood cancer patients
Knowledge-focused CompletedThis study tested whether a swallowable capsule that measures body temperature from inside the body works as well as a standard ear thermometer. It included 30 adults with blood cancer who had low white blood cell counts (neutropenia) and were in the hospital. The goal was to see…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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New PET scan technique reveals how chemotherapy affects lymphoma blood vessels
Knowledge-focused CompletedThis study tested a new type of PET scan (called RGD-K5) to see how blood vessels in lymphoma tumors change after two rounds of chemotherapy. Twenty-one adults with large B-cell lymphoma and a tumor mass larger than 3 cm took part. The goal was to learn more about tumor blood ves…
Phase: PHASE2 • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Blood mutation may reveal hidden lymphoma
Knowledge-focused CompletedThis study looked at whether a specific genetic change (XPO1 E571K) found in the blood of people with classical Hodgkin lymphoma can help doctors find leftover cancer after treatment. Researchers tested blood samples from 137 newly diagnosed patients before and after chemotherapy…
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC