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Tailored radiation boosts lung cancer control in new trial

NCT ID NCT02473133

Completed Disease control Sponsor: Centre Henri Becquerel Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving personalized radiation doses based on PET scans during treatment could improve local control in patients with inoperable stage III non-small cell lung cancer. 158 participants received either standard radiation or a higher, tailored dose to areas still active on scans. The goal was to see if this approach increases the chance of keeping the tumor under control one year after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiation therapy
What this could lead to
If successful, this approach could improve local tumor control and reduce side effects for lung cancer patients by personalizing radiation doses.
What could go wrong
This is a phase 2 trial with only 158 participants, so results may not apply to all patients. The benefit of dose redistribution is uncertain and could increase side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER

Contacts and locations

Locations

  • Centre Henri Becquerel

    Rouen, 76038, France

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