Custom DNA blood test could spot head and neck cancer return

NCT ID NCT03896412

Completed Knowledge-focused Sponsor: Centre Henri Becquerel Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a personalized blood test that looks for tumor DNA in 40 patients with advanced head and neck cancer. The goal was to see if the test could help predict how the disease will progress and detect if the cancer comes back after treatment. Researchers took blood samples before and after surgery and during follow-up to track changes in tumor DNA levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this approach could help doctors better predict outcomes and detect cancer return earlier in head and neck cancer patients.
What could go wrong: This is a small, early-stage study (40 people) focused on feasibility, not treatment. The personalized test may not work for all patients or reliably predict relapse.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK SQUAMOUS CELL CARCINOMA

Contacts and locations

Locations

CHU

Rouen, 76000, France
Centre Henri Becquerel

Rouen, 76000, France

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