Can a fentanyl spray stop pain during cancer radiation?
NCT ID NCT02426697
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 3 trial tested whether a fentanyl spray (Pecfent) could prevent pain when moving patients with bone metastases during radiotherapy. 39 adults with cancer that spread to bone and who had pain during positioning for radiation took part. The study compared fentanyl to a placebo to see if it reduced pain scores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fentanyl transmucosal (Pecfent)
- What this could lead to
- If effective, this could offer a way to prevent pain during radiotherapy sessions for people with bone metastases, making treatment more comfortable.
- What could go wrong
- This is a small, completed Phase 3 trial with only 39 participants, so results may not apply to everyone. Fentanyl is a strong opioid with risks like addiction and side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre Henri Becquerel
Rouen, 76038, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.